Evidence map›Paper›PMID 22008724›Full record

ReviewSeminars in cell & developmental biology2011

Bone Morphogenetic Protein functions as a context-dependent angiogenic cue in vertebrates.

David M Wiley, Suk-Won Jin

Open access · greenAbstract readReview
In one paragraph

Review in Seminars in cell & developmental biology, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed
1.2field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 37 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Article
  6. Transcriptomic analysis identifies novel targets for individual bone morphogenetic protein type 1 receptors in endothelial cells.FASEB journal : official publication of the Federation of American Societies for Experimental Biology · 2021
    Article
  7. Article
  8. The Role of BMP Signaling in Endothelial Heterogeneity.Frontiers in cell and developmental biology · 2021
    Review
  9. Article
  10. Review
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Bone Morphogenetic Proteins.Cold Spring Harbor perspectives in biology · 2016
    Review
  17. Review
  18. The role of BMPs in endothelial cell function and dysfunction.Trends in endocrinology and metabolism: TEM · 2014
    Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

David M WileyMcAllister Heart Institute, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, United States.
Suk-Won Jin
University of North Carolina at Chapel Hill · US

Funding

Endothelial lineage specification and differentiation in vertebrate embryosR01HL090960 · NHLBI · YALE UNIVERSITY · PI JIN, SUK-WON · 2008 to 2013
$2.1M
NHLBI NIH HHS R01 HL090960
6 · The paper itself

Abstract

Bone Morphogenetic Protein (BMP) signaling has been implicated in diverse biological processes. Although how BMP signaling regulates behaviors of endothelial cells during angiogenesis are not fully understood, increasing evidence indicate functions of BMP signaling components are essential in developmental and pathological angiogenesis. Here we review recent advances in delineating the functions of BMP signaling during angiogenesis. In addition, we discuss downstream pathways that transduce BMP signaling in endothelial cells, and factors that modulate BMP signaling response in endothelial cells. Finally, we provide recent insight on how BMP signaling functions as a context dependent angiogenic cue.

Indexed as

AnimalsBone Morphogenetic ProteinsCell DifferentiationEndothelial CellsHumansMorphogenesisNeovascularization, PhysiologicSignal TransductionVertebratesBone Morphogenetic Proteins

Identifiers

PMID22008724
PMCPMC3548572
OpenAlexW2012213575

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.