SynthesisJournal of health services research & policy2012
The Andersen Model of Total Patient Delay: a systematic review of its application in cancer diagnosis.
Synthesis in Journal of health services research & policy, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 290 papers, 22 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
290 citing papers in PubMed, 22 syntheses or guidelines pooled it, 519 citations in OpenAlex.
- Where do delays occur? A systematic review of the barriers to early breast cancer diagnosis across South Africa's health system.BMJ open · 2026Pooled it
- Impact of Surgical Delay on Breast Cancer Prognosis: Systematic Review and Meta-analysis.Annals of surgical oncology · 2026Pooled it
- A systematic review of factors associated with the patient and diagnostic intervals in gastric cancer.Gastric cancer : official journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association · 2026Pooled it
- Barriers to timely diagnosis and treatment of childhood cancer in Sub-Sahara Africa: a qualitative systematic review.BMC cancer · 2025Pooled it
- Implementation of mHealth to support cancer diagnosis in Sub-Saharan Africa: A systematic review.African journal of primary health care & family medicine · 2025Pooled it
- Comparing cancer stage at diagnosis between migrants and non-migrants: a meta-analysis.British journal of cancer · 2025Pooled it
- The effect of time before diagnosis and treatment on colorectal cancer outcomes: systematic review and dose-response meta-analysis.British journal of cancer · 2023Pooled it
- Delay in the diagnosis of paediatric brain tumours: a systematic review.Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2023Pooled it
- Failure to follow up abnormal test results associated with cervical cancer in primary and ambulatory care: a systematic review.BMC cancer · 2023Pooled it
- Delays in seeking, reaching and access to quality cancer care in sub-Saharan Africa: a systematic review.BMJ open · 2023Pooled it
- Duration of the patient interval in breast cancer and factors associated with longer delays in low-and middle-income countries: A systematic review with meta-analysis.Psycho-oncology · 2023Pooled it
- The duration of intervals on the oral cancer care pathway and implications for survival: a systematic review and meta-analysis.Frontiers in public health · 2023Pooled it
- Clinical Delays and Comparative Outcomes in Younger and Older Adults with Colorectal Cancer: A Systematic Review.Current oncology (Toronto, Ont.) · 2022Pooled it
- The patient, diagnostic, and treatment intervals in adult patients with cancer from high- and lower-income countries: A systematic review and meta-analysis.PLoS medicine · 2022Pooled it
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- Psychosocial influences on help-seeking behaviour for cancer in low-income and lower middle-income countries: a mixed-methods systematic review.BMJ global health · 2021Pooled it
- Quality of the diagnostic process in patients presenting with symptoms suggestive of bladder or kidney cancer: a systematic review.BMJ open · 2019Pooled it
- Diagnosis and referral delays in primary care for oral squamous cell cancer: a systematic review.The British journal of general practice : the journal of the Royal College of General Practitioners · 2019Pooled it
- Patient and carer perceived barriers to early presentation and diagnosis of lung cancer: a systematic review.BMC cancer · 2019Pooled it
230 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectivePatient pathways to presentation to health care professionals and initial management in primary care are key determinants of outcomes in cancer. Reducing diagnostic delays may result in improved prognosis and increase the proportion of early stage cancers identified. Investigating diagnostic delay could be facilitated by use of a robust theoretical framework. We systematically reviewed the literature reporting the application of Andersen's Model of Total Patient Delay (delay stages: appraisal, illness, behavioural, scheduling, treatment) in studies which assess cancer diagnosis.
methodsWe searched four electronic databases and conducted a narrative synthesis. Inclusion criteria were studies which: reported primary research, focused on cancer diagnosis and explicitly applied one or more stages of the Andersen Model in the collection or analysis of data.
resultsThe vast majority of studies of diagnostic delay in cancer have not applied a theoretical model to inform data collection or reporting. Ten papers (reporting eight studies) met our inclusion criteria: three studied several cancers. The studies were heterogeneous in their methods and quality. The review confirmed that there are clearly identifiable stages between the recognition of a symptom, first presentation to a health care professional, subsequent diagnosis and initiation of treatment. There was strong evidence to support the existence and importance of appraisal and treatment delay as defined in the Andersen Model, although treatment delay requires expansion. There was some evidence to support scheduling delay which may be contributed to by both patient and the health service. Illness delay was often difficult to distinguish from appraisal delay. It was less clear whether behavioural delay exists as a separate significant stage.
conclusionsGreater consistency is required in the conduct and reporting of studies of diagnostic delay in cancer. We propose refinements to the Andersen Model which could be used to increase its validity and improve the consistency of reporting in future studies.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.