Evidence map›Paper›PMID 22008656›Full record

ArticleAIDS (London, England)2012

Population-based metrics for the timing of HIV diagnosis, engagement in HIV care, and virologic suppression.

Julia C Dombrowski, James B Kent, Susan E Buskin, Joanne D Stekler, Matthew R Golden

Abstract read
In one paragraph

Article in AIDS (London, England), 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 48 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
48citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

48 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
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  17. Measuring the HIV Care Continuum Using Public Health Surveillance Data in the United States.Journal of acquired immune deficiency syndromes (1999) · 2015
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  18. Outcomes of a Clinic-Based Surveillance-Informed Intervention to Relink Patients to HIV Care.Journal of acquired immune deficiency syndromes (1999) · 2015
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Julia C DombrowskiDepartment of Medicine, University of Washington, Seattle, USA. jdombrow@uw.edu
James B Kent
Susan E Buskin
Joanne D Stekler
Matthew R Golden

Funding

VENEREAL DISEASET32AI007140 · NIAID · UNIVERSITY OF WASHINGTON · PI Julia Cook Dombrowski · 1985 to 2026
$19.4M
Clinic and Population-Based Approaches to Retention in HIV CareK23MH090923 · NIMH · UNIVERSITY OF WASHINGTON · PI DOMBROWSKI, JULIA COOK · 2010 to 2014
$657k
NIAID NIH HHS L30 AI084504NIAID NIH HHS T32 AI007140NIMH NIH HHS 5K23MH090923-01NIMH NIH HHS K23 MH090923NIMH NIH HHS L30 MH095060
6 · The paper itself

Abstract

objectiveTo compare population-based metrics for assessing progress toward the US National HIV/AIDS Strategy (NHAS) goals.

designAnalysis of surveillance data from persons living with HIV/AIDS (PLWHA) in King County, Washington, USA, 2005-2009.

methodsWe examined indicators of the timing of HIV diagnosis [intertest interval, CD4 cell count at diagnosis, and AIDS ≤ 1 year of diagnosis (late diagnosis)]; linkage to initial care (CD4 or viral load report ≤3 months after diagnosis) and sustained care (a laboratory report 3-9 months after linkage); engagement in continuous care in 2009 (at least two laboratory reports ≥3 months apart); and virologic suppression.

resultsThirty-two percent of persons had late HIV diagnoses, 31% of whom reported testing HIV negative in the 2 years preceding their HIV diagnoses. Linkage to sustained care, but not linkage to initial care, was significantly associated with subsequent virologic suppression. Among 6070 PLWHA in King County, 65% of those with at least one viral load reported in 2009 and 53% of all PLWHA had virologic suppression. Although only 66% of all PLWHA were engaged in continuous care, 81% were defined as engaged using the denominator proposed in the NHAS (at least one laboratory result reported in 2009 excluding persons establishing care in the second half of the year).

conclusionsProposed metrics for monitoring the HIV care continuum may not accurately measure late diagnoses or linkage to sustained care and are sensitive to assumptions about the size of the population of PLWHA. Monitoring progress toward achievement of NHAS goals will require improvements in HIV surveillance data and refinement of care metrics.

Indexed as

HIV-1Population SurveillanceViral LoadAcquired Immunodeficiency SyndromeAdultAnalysis of VarianceAnti-HIV AgentsCD4 Lymphocyte CountData CollectionFemaleHIV InfectionsHumansIncidenceMalePublic HealthWashingtonAnti-HIV Agents

Identifiers

PMID22008656
PMCPMC3434867

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.