ArticleAnnals of internal medicine2011
Comparative effectiveness of digital versus film-screen mammography in community practice in the United States: a cohort study.
Article in Annals of internal medicine, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 120 papers, 4 of them syntheses that pooled it.
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Who cites it
120 citing papers in PubMed, 4 syntheses or guidelines pooled it, 267 citations in OpenAlex.
- Mammographic breast density and the risk of breast cancer: A systematic review and meta-analysis.Breast (Edinburgh, Scotland) · 2022Pooled it
- Impact of Full-Field Digital Mammography Versus Film-Screen Mammography in Population Screening: A Meta-Analysis.Journal of the National Cancer Institute · 2021Pooled it
- Benefits and Harms of Screening Mammography by Comorbidity and Age: A Qualitative Synthesis of Observational Studies and Decision Analyses.Journal of general internal medicine · 2016Pooled it
- Guideline
- Geographic variation in volumetric breast density between screening regions in the Netherlands.European radiology · 2015Trial
- Mammographic quantitative image analysis and biologic image composition for breast lesion characterization and classification.Medical physics · 2014Trial
- Mammographic screening detects low-risk tumor biology breast cancers.Breast cancer research and treatment · 2014Trial
- Effect of an annotation-free artificial intelligence system for simultaneous detection and diagnosis on breast ultrasonography: a multireader, multicase study across diverse healthcare professionals.Ultrasonography (Seoul, Korea) · 2026Article
- Generative AI-Enhanced Microcalcification Detection in Full-Field Digital Mammography: Reducing False Positives with High Sensitivity.Research square · 2025Article
- Challenges and variability in breast cancer screening: diagnostic work-up and strategies for standardization across Europe.European radiology · 2025Article
- Multicancer early detection testing: Guidance for primary care discussions with patients.Cancer · 2025Review
- Current Concepts in Molecular Breast Imaging.Journal of breast imaging · 2025Review
- Do women with a history of breast cancer recommend risk-based breast cancer screening? An in-depth interview study.Frontiers in psychology · 2025Article
- A Retrospective Chart Analysis Comparing Breast Cancer Detection Rates Between Annual Versus Biennial Mammograms.Journal of clinical medicine research · 2024Article
- Benefits and Harms of Mammography Screening in 75 + Women to Inform Shared Decision-making: a Simulation Modeling Study.Journal of general internal medicine · 2024Article
- Multiview deep learning networks based on automated breast volume scanner images for identifying breast cancer in BI-RADS 4.Frontiers in oncology · 2024Article
- Knowledge, attitude, and practice towards breast self-examination among women: a web based community study.Frontiers in public health · 2024Article
- Tumor-derived EV miRNA signatures surpass total EV miRNA in supplementing mammography for precision breast cancer diagnosis.Theranostics · 2024Article
- Sociodemographic Variations in Women's Reports of Discussions With Clinicians About Breast Density.JAMA network open · 2023Article
- Review
60 more citing papers are in PubMed but not listed here.
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Authors and funding
9 authors at 2 institutions in 1 country.
Funding
Abstract
backgroundFew studies have examined the comparative effectiveness of digital versus film-screen mammography in U.S. community practice.
objectiveTo determine whether the interpretive performance of digital and film-screen mammography differs.
designProspective cohort study.
settingMammography facilities in the Breast Cancer Surveillance Consortium.
participants329,261 women aged 40 to 79 years underwent 869 286 mammograms (231 034 digital; 638 252 film-screen). MEASUREMENTS: Invasive cancer or ductal carcinoma in situ diagnosed within 12 months of a digital or film-screen examination and calculation of mammography sensitivity, specificity, cancer detection rates, and tumor outcomes.
resultsOverall, cancer detection rates and tumor characteristics were similar for digital and film-screen mammography, but the sensitivity and specificity of each modality varied by age, tumor characteristics, breast density, and menopausal status. Compared with film-screen mammography, the sensitivity of digital mammography was significantly higher for women aged 60 to 69 years (89.9% vs. 83.0%; P = 0.014) and those with estrogen receptor-negative cancer (78.5% vs. 65.8%; P = 0.016); borderline significantly higher for women aged 40 to 49 years (82.4% vs. 75.6%; P = 0.071), those with extremely dense breasts (83.6% vs. 68.1%; P = 0.051), and pre- or perimenopausal women (87.1% vs. 81.7%; P = 0.057); and borderline significantly lower for women aged 50 to 59 years (80.5% vs. 85.1%; P = 0.097). The specificity of digital and film-screen mammography was similar by decade of age, except for women aged 40 to 49 years (88.0% vs. 89.7%; P < 0.001). LIMITATION: Statistical power for subgroup analyses was limited.
conclusionOverall, cancer detection with digital or film-screen mammography is similar in U.S. women aged 50 to 79 years undergoing screening mammography. Women aged 40 to 49 years are more likely to have extremely dense breasts and estrogen receptor-negative tumors; if they are offered mammography screening, they may choose to undergo digital mammography to optimize cancer detection. PRIMARY FUNDING SOURCE: National Cancer Institute.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.