ArticleProceedings of the National Academy of Sciences of the United States of America2011
Sex-linked transcription factor involved in a shift of sex-pheromone preference in the silkmoth Bombyx mori.
Article in Proceedings of the National Academy of Sciences of the United States of America, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
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Who cites it
13 citing papers in PubMed.
- Gustatory receptors interact with the serotonin pathway to regulate silkmoth stereotyped courtship behavior.BMC biology · 2025Article
- Neurological confirmation of periplanone-D exploitation as a primary sex pheromone and counteractions of other components in the smoky brown cockroach Periplaneta fuliginosa.Cell and tissue research · 2025Article
- Olfactory Receptor Gene Regulation in Insects: Multiple Mechanisms for Singular Expression.Frontiers in neuroscience · 2021Review
- Within-population variability in a moth sex pheromone blend, part 2: selection towards fixation.Royal Society open science · 2019Article
- Evaluation and hedonic value in mate choice.Current zoology · 2018Article
- Differential gene expression in the evolution of sex pheromone communication in New Zealand's endemic leafroller moths of the genera Ctenopseustis and Planotortrix.BMC genomics · 2018Article
- The morphology of antennal lobe projection neurons is controlled by a POU-domain transcription factor Bmacj6 in the silkmoth Bombyx mori.Scientific reports · 2017Article
- Genetic mapping of male pheromone response in the European corn borer identifies candidate genes regulating neurogenesis.Proceedings of the National Academy of Sciences of the United States of America · 2016Article
- Sensillar expression and responses of olfactory receptors reveal different peripheral coding in two Helicoverpa species using the same pheromone components.Scientific reports · 2016Article
- Establishment of tools for neurogenetic analysis of sexual behavior in the silkmoth, Bombyx mori.PloS one · 2014Article
- Molecular and neural mechanisms of sex pheromone reception and processing in the silkmoth Bombyx mori.Frontiers in physiology · 2014Review
- Functional specificity of sex pheromone receptors in the cotton bollworm Helicoverpa armigera.PloS one · 2013Article
- Single mutation to a sex pheromone receptor provides adaptive specificity between closely related moth species.Proceedings of the National Academy of Sciences of the United States of America · 2012Article
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10 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
In the sex-pheromone communication systems of moths, odorant receptor (Or) specificity as well as higher olfactory information processing in males should be finely tuned to the pheromone of conspecific females. Accordingly, male sex-pheromone preference should have diversified along with the diversification of female sex pheromones; however, the genetic mechanisms that facilitated the diversification of male preference are not well understood. Here, we explored the mechanisms involved in a drastic shift in sex-pheromone preference in the silkmoth Bombyx mori using spli mutants in which the genomic structure of the gene Bmacj6, which encodes a class IV POU domain transcription factor, is disrupted or its expression is repressed. B. mori females secrete an ∼11:1 mixture of bombykol and bombykal. Bombykol alone elicits full male courtship behavior, whereas bombykal alone shows no apparent activity. In the spli mutants, the behavioral responsiveness of males to bombykol was markedly reduced, whereas bombykal alone evoked full courtship behavior. The reduced response of spli males to bombykol was explained by the paucity of bombykol receptors on the male antennae. It was also found that, in the spli males, neurons projecting into the toroid, a compartment in the brain where bombykol receptor neurons normally project, responded strongly to bombykal. The present study highlights a POU domain transcription factor, Bmacj6, which may have caused a shift of sex-pheromone preference in B. mori through Or gene choice and/or axon targeting.
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