Evidence map›Paper›PMID 22006170›Full record

ReviewCurrent rheumatology reports2012

Dendritic cells: novel players in fibrosis and scleroderma.

Theresa T Lu

Abstract readReview
In one paragraph

Review in Current rheumatology reports, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.

0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

26 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. LangerinClinical, cosmetic and investigational dermatology · 2025
    Review
  5. Cadherin-11 targeted cell-specific liposomes enabled skin fibrosis treatment by inducing apoptosis.Journal of controlled release : official journal of the Controlled Release Society · 2024
    Article
  6. Review
  7. Review
  8. Article
  9. Article
  10. Article
  11. Upcoming treatments for morphea.Immunity, inflammation and disease · 2021
    Review
  12. Immune and repair responses in joint tissues and lymph nodes after knee arthroplasty surgery in mice.Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research · 2021
    Article
  13. Article
  14. The Roles of Immune Cells in the Pathogenesis of Fibrosis.International journal of molecular sciences · 2020
    Review
  15. Review
  16. Article
  17. Bone Marrow CD11c+ Cell-Derived Amphiregulin Promotes Pulmonary Fibrosis.Journal of immunology (Baltimore, Md. : 1950) · 2016
    Article
  18. Review
  19. Update on macrophages and innate immunity in scleroderma.Current opinion in rheumatology · 2015
    Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author.

Theresa T LuAutoimmunity and Inflammation Program and Pediatric Rheumatology, Hospital for Special Surgery, New York, NY 10021, USA. lut@hss.edu

Funding

Vascular-stromal function and regulation in immunityR01AI079178 · NIAID · HOSPITAL FOR SPECIAL SURGERY · PI Theresa T. Lu · 2010 to 2026
$6.6M
NIAID NIH HHS R01 AI079178
6 · The paper itself

Abstract

Dendritic cells are professional antigen-presenting cells that are most studied for their function in mediating T-cell tolerance and T-cell activation. In addition, recent evidence indicates that dendritic cells can regulate the vasculature and function of fibroblast-type cells. The potential contribution of dendritic cells to scleroderma and fibrosis is not well-understood. In this article, we review recent studies as well as describe our own ongoing work that points toward a role for dendritic cells in scleroderma and fibrosis.

Indexed as

Dendritic CellsFibrosisHumansKidneyLiverLungScleroderma, SystemicSkin

Identifiers

PMID22006170
PMCPMC5815163

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.