Evidence map›Paper›PMID 22006065›Full record

ReviewCurrent allergy and asthma reports2012

Latitude, sunlight, vitamin D, and childhood food allergy/anaphylaxis.

Raymond James Mullins, Carlos A Camargo

Open access · bronzeAbstract readReview
PubMed Publisher
In one paragraph

Review in Current allergy and asthma reports, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed
3.2field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 57 citations in OpenAlex.

  1. Trial
  2. Vitamin D, virus etiology, and atopy in first-time wheezing children in Finland.Pediatric allergy and immunology : official publication of the European Society of Pediatric Allergy and Immunology · 2014
    Trial
  3. Article
  4. Article
  5. Article
  6. Beneficial health effects of ultraviolet radiation: expert review and conference report.Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology · 2025
    Review
  7. Article
  8. Article
  9. Review
  10. A Clinical Study to Evaluate the Role of Vitamin D3 in Allergic Rhinitis.Indian journal of otolaryngology and head and neck surgery : official publication of the Association of Otolaryngologists of India · 2022
    Article
  11. Review
  12. An Overview of Environmental Risk Factors for Food Allergy.International journal of environmental research and public health · 2022
    Review
  13. The Influence of Sunlight Exposure and Sun Protecting Behaviours on Allergic Outcomes in Early Childhood.International journal of environmental research and public health · 2021
    Article
  14. Article
  15. Review
  16. Article
  17. Primary Prevention of Food Allergy.Current allergy and asthma reports · 2017
    Review
  18. Review
  19. Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 2 countries.

Raymond James MullinsMedical School, Australian National University, Canberra, ACT, Australia. rmullins@allergycapital.com.au
Carlos A Camargo
Harvard University · USUniversity of Canberra · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Vitamin D is widely known for its role in bone metabolism, but this sterol hormone also has important immunomodulatory properties. Vitamin D is produced by the conversion of D3 in the skin following UVB exposure, or after ingestion of D2 or D3. At the extremes of latitude, there is insufficient UVB intensity in the autumn and winter months for adequate synthesis of vitamin D to occur. Growing evidence implicates vitamin D deficiency in early life in the pathogenesis of nonskeletal disorders (e. g., type 1 diabetes and multiple sclerosis) and, more recently, atopic disorders. Several studies have reported higher rates of food allergy/anaphylaxis or proxy measures at higher absolute latitudes. Although causality remains to be determined, these studies suggest a possible role for sunlight and/or vitamin D in the pathogenesis of food allergy/anaphylaxis.

Indexed as

AnaphylaxisCausalityComorbidityDiabetes Mellitus, Type 1Food HypersensitivityHumansIncidenceMultiple SclerosisSeasonsSkinSunlightUltraviolet RaysUnited StatesVitamin DVitamin D DeficiencyVitamin D

Identifiers

PMID22006065
OpenAlexW1964215386

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.