ArticleAntimicrobial agents and chemotherapy2012
Effect of usnic acid on Candida orthopsilosis and C. parapsilosis.
Article in Antimicrobial agents and chemotherapy, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
16 citing papers in PubMed, 42 citations in OpenAlex.
- Lichen and Its Microbiome as an Untapped Source of Anti-Biofilm Compounds.Chemistry & biodiversity · 2025Review
- Controlling Oral Polymicrobial Biofilm Using Usnic Acid on the Surface of Titanium in the Artificial Saliva Media.Antibiotics (Basel, Switzerland) · 2025Article
- The lichen secondary metabolite lichesterinic acid exhibits antibiofilm activity against fungal pathogens.Frontiers in cellular and infection microbiology · 2025Article
- Development, Optimization, and Evaluation of New Gel Formulations with Cyclodextrin Complexes and Volatile Oils with Antimicrobial Activity.Gels (Basel, Switzerland) · 2024Article
- Usnic Acid-Loaded Magnetite Nanoparticles-A Comparative Study between Synthesis Methods.Molecules (Basel, Switzerland) · 2023Article
- Effectiveness of a Self-Decontaminating Coating Containing Usnic Acid in Reducing Environmental Microbial Load in Tertiary-Care Hospitals.International journal of environmental research and public health · 2023Article
- Antimicrobial Effectiveness of an Usnic-Acid-Containing Self-Decontaminating Coating on Underground Metro Surfaces in Athens.Microorganisms · 2022Article
- Quatsomes Formulated with l-Prolinol-Derived Surfactants as Antibacterial Nanocarriers of (+)-Usnic Acid with Antioxidant Activity.ACS applied nano materials · 2022Article
- Phytochemical composition, antimicrobial activities, and cholinesterase inhibitory properties of the lichenFrontiers in chemistry · 2022Article
- Antimicrobial and antioxidant activity of Evernia prunastri extracts and their isolates.World journal of microbiology & biotechnology · 2021Article
- Lichen Polyphenolic Compounds for the Eradication ofFrontiers in cellular and infection microbiology · 2021Article
- A Two-Way Road: Antagonistic Interaction Between Dual-Species Biofilms Formed byFrontiers in microbiology · 2020Article
- Design, synthesis and antimicrobial activity of usnic acid derivatives.MedChemComm · 2018Article
- Antifungal and Anti-Biofilm Activities of Acetone Lichen Extracts against Candida albicans.Molecules (Basel, Switzerland) · 2017Article
- Antifungal Compounds againstBioMed research international · 2017Review
- Water soluble usnic acid-polyacrylamide complexes with enhanced antimicrobial activity against Staphylococcus epidermidis.International journal of molecular sciences · 2013Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The activity of usnic acid against Candida orthopsilosis and Candida parapsilosis on planktonic and biofilm conditions was investigated by using a broth microdilution and microplate methods. Potent in vitro activities against different Candida species were obtained. The metabolic activity of sessile cells of C. parapsilosis complex was reduced by 80% at four times the 80% inhibitory concentration. The in vitro studies support further efforts to determine whether usnic acid can be used clinically to cure patients with Candida infections.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.