Trial reportThe Journal of physiology2011
Sex modulates whole-body sudomotor thermosensitivity during exercise.
Trial report in The Journal of physiology, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 45 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
45 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Seasonal Heat Acclimatisation in Healthy Adults: A Systematic Review.Sports medicine (Auckland, N.Z.) · 2022Pooled it
- Exploring the mechanisms underpinning sweating: the development of a specialized ventilated capsule for use with intradermal microdialysis.Physiological reports · 2016Trial
- Thermoregulation and Hydration Dynamics in a 160-km Ultra-Endurance Race in a Tropical Environment: A Field Study on 80 Runners.Sports medicine (Auckland, N.Z.) · 2026Article
- Repeated Sprint Training in Heat Improves Repeated Sprint Ability Under Temperate Conditions Similarly in Active Males and Females.European journal of sport science · 2026Article
- Defining Sex- and Age-Specific Initial Stay Times for Continuous Moderate-Intensity Work in Hot Environments Before Heat-Mitigation Controls Are Implemented - Part A.American journal of industrial medicine · 2025Article
- Real-Time Monitoring of Biometric Responses During a 200-km Ultra-Endurance Race Across the Desert.European journal of sport science · 2025Observational
- Influence of Sex on Whole-Body Heat Exchange Following Cold Beverage Ingestion During Work-Rest Cycles in the Heat.American journal of industrial medicine · 2025Article
- Sex-differences in Mountain Ultra-trail Performance: Look at the Scenery.Sports medicine - open · 2025Article
- Article
- Facial cooling improves thermal perceptions and maintains the interleukin-6 response during passive heating: A sex comparison.Temperature (Austin, Tex.) · 2025Article
- Humans exercising in the heat: A review on sweat models and a comparison to recent experimental datasets.Temperature (Austin, Tex.) · 2025Article
- Mapping the evidence on the impact of heat stress on exercise and work performance in females: a scoping review.Frontiers in physiology · 2025Review
- Customizing individual heat mitigation strategies to optimize performance in elite athletes.Frontiers in physiology · 2025Review
- Effects of individual characteristics and local body functions on sweating response: A review.International journal of biometeorology · 2024Review
- Effect of hyperthermia on simulated muscle activation in female when crossing obstacle.Scientific reports · 2024Article
- Indoor overheating: A review of vulnerabilities, causes, and strategies to prevent adverse human health outcomes during extreme heat events.Temperature (Austin, Tex.) · 2024Review
- Associations between medium- and long-term exposure to air temperature and epigenetic age acceleration.Environment international · 2023Article
- High ambient temperature increases the number of emergency visits for upper urolithiasis in Hefei City, China.Heliyon · 2023Article
- Human temperature regulation under heat stress in health, disease, and injury.Physiological reviews · 2022Review
- Heat Acclimation in Females Does Not Limit Aerobic Exercise Training Outcomes.International journal of environmental research and public health · 2022Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
It is unclear whether true physiological differences exist in temperature regulation between males and females during exercise, independently of differences in physical characteristics and metabolic heat production. Therefore, we examined differences in the onset threshold and thermosensitivity of whole-body sudomotor activity and cutaneous vascular conductance between males and females matched for body mass and surface area. Nine males and nine females performed 90 min of exercise at each of the following intensities in a warm/dry environment: 50% of maximum oxygen consumption (V(O(2)max)) and at a fixed rate of metabolic heat production equal to 500 W. Evaporative heat loss (EHL, direct calorimetry) and cutaneous vascular conductance (CVC, laser-Doppler) were measured continuously. Mean body temperature was calculated from the measurements of oesophageal and mean skin temperatures. During exercise at 50% V(O(2)max), a lower rate of sudomotor activity was observed in females (385 ± 12 vs. 512 ± 24 W, P < 0.001). However, irrespective of sex, individual EHL values were strongly associated with metabolic heat production (R(2) = 0.82, P < 0.001). Nonetheless, a lower rate of EHL was observed in females when exercise was performed at 500 W of metabolic heat production (419 ± 7 vs. 454 ± 11 W, P = 0.032). Furthermore, a lower increase in EHL per increase in mean body temperature was observed in females (553 ± 77 vs. 795 ± 85 W °C(-1), P = 0.051), with no differences in the onset threshold (36.77 ± 0.06 vs. 36.61 ± 0.11°C, P = 0.242). In contrast, no differences were observed in CVC. Collectively, these findings demonstrate that females have a lower thermosensitivity of the whole-body sudomotor response compared to males during exercise in the heat performed at a fixed rate of metabolic heat production.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.