ReviewSexual development : genetics, molecular biology, evolution, endocrinology, embryology, and pathology of sex determination and differentiation2012
Gonadal and sex differentiation abnormalities of dogs and cats.
Review in Sexual development : genetics, molecular biology, evolution, endocrinology, embryology, and pathology of sex determination and differentiation, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
24 citing papers in PubMed.
- Canine XX Disorders/Differences of Sex Development (SRY-Negative): A Potential Role for theSexual development : genetics, molecular biology, evolution, endocrinology, embryology, and pathology of sex determination and differentiation · 2026Review
- Computed Tomographic and Ultrasonographic Features in Three Dogs with Infected Uterus Masculinus and Concurrent Genital Neoplasia.Animals : an open access journal from MDPI · 2025Article
- "My Bitch Is Empty!" an Overview of the Preconceptional Causes of Infertility in Dogs.Veterinary sciences · 2025Review
- XY disorder of sexual development in a dog: a case study by histopathology, genotyping and karyotyping.Veterinary research communications · 2025Article
- Genomic Sequencing to Detect Cross-Breeding Quality in Dogs: An Example Studying Disorders in Sexual Development.International journal of molecular sciences · 2024Article
- Specificity of Key Sex Determination Genes in a Mammal with Ovotestes: The European MoleAnimals : an open access journal from MDPI · 2024Article
- Influence of dietary supplementation withFrontiers in veterinary science · 2024Article
- Simultaneous Occurrence of Hypospadias and Bilateral Cleft Lip and Jaw in a Crossbred Calf: Clinical, Computer Tomographic, and Genomic Characterization.Animals : an open access journal from MDPI · 2023Article
- An Unusual Case of Collision Testicular Tumor in a Female DSD Dog.Veterinary sciences · 2023Article
- Non-mosaic X monosomy (77,X) in a female dog with signs of virilization.Journal of applied genetics · 2023Article
- Disorders of sexual development in the cat: Current state of knowledge and diagnostic approach.Journal of feline medicine and surgery · 2022Review
- Case Report: Disorder of Sexual Development in a Chinese Crested Dog With XX/XY Leukocyte Chimerism and Mixed Cell Testicular Tumors.Frontiers in veterinary science · 2022Article
- Clinical Cytogenetics of the Dog: A Review.Animals : an open access journal from MDPI · 2021Review
- Article
- Dog Steroidogenic Factor-1: Molecular cloning and analysis of epigenetic regulation.The Journal of veterinary medical science · 2020Article
- Pluripotent Cell Models for Gonadal Research.International journal of molecular sciences · 2019Review
- AMH and AMHR2 mutations: A spectrum of reproductive phenotypes across vertebrate species.Developmental biology · 2019Review
- Article
- Hypoluteoidism in a dog associated with recurrent mammary fibroadenoma stimulated by progestin therapy.Acta veterinaria Scandinavica · 2017Article
- Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
1 author.
Funding
Abstract
The molecular steps in normal sexual development were largely discovered by studying patients and animal models with disorders of sexual development (DSD). Although several types of DSD have been reported in the cat and dog, which are often strikingly similar to human DSD, these have been infrequently utilized to contribute to our knowledge of mammalian sexual development. Canine and feline cases of DSD with sufficient evidence to be considered as potential models are summarized in this report. The consensus DSD terminology, and reference to previous terminology, is used to foster adoption of a common nomenclature that will facilitate communication and collaboration between veterinarians, physicians, and researchers. To efficiently utilize these unique resources as molecular tools continue to improve, it will be helpful to deposit samples from valuable cases into repositories where they are available to contribute to our understanding of sexual development, and thus improve human and animal health.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.