ArticleFuture medicinal chemistry2011
Medicinal chemistry for 2020.
Article in Future medicinal chemistry, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
11 citing papers in PubMed.
- Medicinal Chemistry Advancement in Life-Threatening Diseases.Current topics in medicinal chemistry · 2025Article
- A dual diffusion model enables 3D molecule generation and lead optimization based on target pockets.Nature communications · 2024Article
- Development of New Potential Inhibitors of β1 Integrins through In Silico Methods-Screening and Computational Validation.Life (Basel, Switzerland) · 2022Article
- Rhinacanthin-C but Not -D Extracted fromPharmaceuticals (Basel, Switzerland) · 2022Article
- AI-Driven Synthetic Route Design Incorporated with Retrosynthesis Knowledge.Journal of chemical information and modeling · 2022Article
- CompRet: a comprehensive recommendation framework for chemical synthesis planning with algorithmic enumeration.Journal of cheminformatics · 2020Article
- Rethinking drug design in the artificial intelligence era.Nature reviews. Drug discovery · 2020Review
- Expanding the medicinal chemistry synthetic toolbox.Nature reviews. Drug discovery · 2018Review
- Automating drug discovery.Nature reviews. Drug discovery · 2018Review
- Surfing the Protein-Protein Interaction Surface Using Docking Methods: Application to the Design of PPI Inhibitors.Molecules (Basel, Switzerland) · 2015Review
- A molecular-modeling toolbox aimed at bridging the gap between medicinal chemistry and computational sciences.International journal of molecular sciences · 2013Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
Abstract
Rapid advances in our collective understanding of biomolecular structure and, in concert, of biochemical systems, coupled with developments in computational methods, have massively impacted the field of medicinal chemistry over the past two decades, with even greater changes appearing on the horizon. In this perspective, we endeavor to profile some of the most prominent determinants of change and speculate as to further evolution that may consequently occur during the next decade. The five main angles to be addressed are: protein-protein interactions; peptides and peptidomimetics; molecular diversity and pharmacological space; molecular pharmacodynamics (significance, potential and challenges); and early-stage clinical efficacy and safety. We then consider, in light of these, the future of medicinal chemistry and the educational preparation that will be required for future medicinal chemists.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.