ReviewJournal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine2011
Behavioral and genetic markers of sleepiness.
Review in Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
22 citing papers in PubMed, 42 citations in OpenAlex.
- Poorer objective but not subjective driving performance in drivers vulnerable to sleep loss effects during extended wake.Journal of sleep research · 2025Article
- Sex Differences in the Role of Sleep on Cognition in Older Adults.medRxiv : the preprint server for health sciences · 2024Article
- Sex differences in the role of sleep on cognition in older adults.Sleep advances : a journal of the Sleep Research Society · 2024Article
- Modeling resilience to sleep disruption to study resistance to Alzheimer's disease.Aging pathobiology and therapeutics · 2023Article
- Foreword: Festschrift in honor of David Dinges, scientist and mentor extraordinaire.Sleep advances : a journal of the Sleep Research Society · 2023Article
- Resilience to acute sleep deprivation is associated with attenuation of hippocampal mediated learning impairment.Aging pathobiology and therapeutics · 2020Article
- Review
- Effects of Sleep Deprivation on Surgeons Dexterity.Frontiers in neurology · 2019Review
- Neurobehavioral Effects and Biomarkers of Sleep Loss in Healthy Adults.Current neurology and neuroscience reports · 2017Review
- Longitudinal Outcomes of Start Time Delay on Sleep, Behavior, and Achievement in High School.Sleep · 2016Article
- Article
- Cumulative neurobehavioral and physiological effects of chronic caffeine intake: individual differences and implications for the use of caffeinated energy products.Nutrition reviews · 2014Review
- Correlation of daytime sleepiness with urine metabolites in patients with obstructive sleep apnea.Sleep & breathing = Schlaf & Atmung · 2014Article
- Sleepiness and Safety: Where Biology Needs Technology.Sleep and biological rhythms · 2014Article
- Habitual sleep duration associated with self-reported and objectively determined cardiometabolic risk factors.Sleep medicine · 2014Article
- Neuroimaging, cognition, light and circadian rhythms.Frontiers in systems neuroscience · 2014Review
- Sleep deprivation and neurobehavioral dynamics.Current opinion in neurobiology · 2013Review
- Circadian rhythms, sleep deprivation, and human performance.Progress in molecular biology and translational science · 2013Review
- Article
- Predicting Risk in Space: Genetic Markers for Differential Vulnerability to Sleep Restriction.Acta astronautica · 2012Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 1 country.
Funding
Abstract
Neurobehavioral responses to acute total and chronic partial sleep deprivation occur in healthy adults and are particularly evident in vigilant attention performance. There are large inter-individual differences in the degree of cognitive deficits--such differences are manifested in proportionality between the mean and variance as sleep loss progresses. It has recently been demonstrated via laboratory experiments that differential neurobehavioral vulnerability to sleep deprivation is not random--but rather is stable and trait-like--strongly suggesting a phenotypic response with possible genotypic involvement. These experiments also showed that vulnerability was not explained by subjects' baseline functioning or a number of other potential predictors. Differential vulnerability has been shown to extend to chronic partial sleep deprivation. One potential genetic biomarker for such differential vulnerability is the human leukocyte antigen (HLA) DQB1*0602, an allele which we recently demonstrated predicts interindividual differences in sleepiness, physiological sleep, and fatigue to chronic partial sleep deprivation in healthy adults. Determination of biomarkers of individual differences to sleep loss will help identify those individuals in the general population who are most in need of prevention of sleep debt and in need of effective countermeasures for sleep loss; will further understanding and management of vulnerability to excessive sleepiness due to common sleep and medical disorders; and will inform public policies pertaining to the need for adequate sleep.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.