ReviewExperimental physiology2012
Human investigations into the arterial and cardiopulmonary baroreflexes during exercise.
Review in Experimental physiology, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 80 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
80 citing papers in PubMed.
- Set configuration influences cardiovascular responses to resistance exercise in postmenopausal females in a randomized crossover trial from the CARE project.Scientific reports · 2025Trial
- Green Exercise: Can Nature Video Benefit Isometric Exercise?International journal of environmental research and public health · 2021Trial
- Metaboreflex activation delays heart rate recovery after aerobic exercise in never-treated hypertensive men.The Journal of physiology · 2016Trial
- High-intensity intermittent exercise and cardiovascular and autonomic function.Clinical autonomic research : official journal of the Clinical Autonomic Research Society · 2013Trial
- Greater muscle mass does not affect peripheral hypercapnic chemosensitivity during exercise in healthy adults.Physiological reports · 2026Article
- Oxidative stress and impaired cardiovagal baroreflex sensitivity in young adults with post-traumatic stress disorder.Experimental physiology · 2026Article
- The role of αAmerican journal of physiology. Heart and circulatory physiology · 2025Article
- The effects of limb suction during arterial occlusion on arterial baroreflex in humans.American journal of physiology. Heart and circulatory physiology · 2025Article
- The effect of slow breathing on cardiovascular and electromyographic responses during standing perturbations in older adults.European journal of ageing · 2025Article
- Dissecting the exercise pressor reflex in heart failure: A multi-step failure.Autonomic neuroscience : basic & clinical · 2025Review
- Cardiac baroreflex sensitivity during repeated handgrip exercise: Comparisons with sit-stand maneuvers and spontaneous rest.Physiological reports · 2025Article
- Abnormal cardiovascular control during exercise: Role of insulin resistance in the brain.Autonomic neuroscience : basic & clinical · 2025Review
- Acute isometric and dynamic exercise do not alter cerebral sympathetic nerve activity in healthy humans.Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism · 2024Article
- Blood pressure and heart rate variability to assess autonomic response to an acute bout of high intensity interval exercise in healthy young adults.Physiological reports · 2024Article
- Advancements in the neurocirculatory reflex response to hypoxia.American journal of physiology. Regulatory, integrative and comparative physiology · 2024Review
- Influence of sex on sympathetic vasomotor outflow responses to passive leg raising in young individuals.The journal of physiological sciences : JPS · 2024Article
- Baroreflex sensitivity and its implication in neurally mediated syncope in children.World journal of pediatrics : WJP · 2023Article
- Neural control of the circulation during exercise in heart failure with reduced and preserved ejection fraction.American journal of physiology. Heart and circulatory physiology · 2023Review
- Autonomic cardiovascular control during exercise.American journal of physiology. Heart and circulatory physiology · 2023Review
- Cardiorespiratory dynamics during respiratory maneuver in athletes.Frontiers in network physiology · 2023Article
20 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
Abstract
After considerable debate and key experimental evidence, the importance of the arterial baroreflex in contributing to and maintaining the appropriate neural cardiovascular adjustments to exercise is now well accepted. Indeed, the arterial baroreflex resets during exercise in an intensity-dependent manner to continue to regulate blood pressure as effectively as at rest. Studies have indicated that the exercise resetting of the arterial baroreflex is mediated by both the feedforward mechanism of central command and the feedback mechanism associated with skeletal muscle afferents (the exercise pressor reflex). Another perhaps less appreciated neural mechanism involved in evoking and maintaining neural cardiovascular responses to exercise is the cardiopulmonary baroreflex. The limited information available regarding the cardiopulmonary baroreflex during exercise provides evidence for a role in mediating sympathetic nerve activity and blood pressure responses. In addition, recent investigations have demonstrated an interaction between cardiopulmonary baroreceptors and the arterial baroreflex during dynamic exercise, which contributes to the magnitude of exercise-induced increases in blood pressure as well as the resetting of the arterial baroreflex. Furthermore, neural inputs from the cardiopulmonary baroreceptors appear to play an important role in establishing the operating point of the arterial baroreflex. This symposium review highlights recent studies in these important areas indicating that the interactions of four neural mechanisms (central command, the exercise pressor reflex, the arterial baroreflex and cardiopulmonary baroreflex) are integral in mediating the neural cardiovascular adjustments to exercise.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.