ReviewJournal of applied genetics2012
Current genetic methodologies in the identification of disaster victims and in forensic analysis.
Review in Journal of applied genetics, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 38 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
38 citing papers in PubMed, 165 citations in OpenAlex.
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- From Jane Doe to Sofia: DNA Extraction Protocol from Bones and Teeth without Liquid Nitrogen for Identifying Skeletal Remains.International journal of molecular sciences · 2024Article
- Why identification matters: an explorative study on six cases of family reunification.International journal of legal medicine · 2024Article
- Identification of the Remains of an Adult Using DNA from Their Deciduous Teeth as a Reference Sample.Medicina (Kaunas, Lithuania) · 2023Article
- Palatal Rugae Patterns in Fars, Turkmen, and Sistani Ethnicities in the Eastern Part of the Caspian Littoral of Iran.Diagnostics (Basel, Switzerland) · 2023Article
- Review
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- Intra-bone nuclear DNA variability and STR typing success in Second World War first ribs.International journal of legal medicine · 2021Article
- Intra-bone nuclear DNA variability in Second World War metatarsal and metacarpal bones.International journal of legal medicine · 2021Article
- Human identification: a review of methods employed within an Australian coronial death investigation system.International journal of legal medicine · 2021Article
- A Novel Panel of 43 Insertion/Deletion Loci for Human Identifications of Forensic Degraded DNA Samples: Development and Validation.Frontiers in genetics · 2021Article
- Nails as a primary sample type for molecular genetic identification of highly decomposed human remains.International journal of legal medicine · 2020Article
- Forensic DNA Profiling: Autosomal Short Tandem Repeat as a Prominent Marker in Crime Investigation.The Malaysian journal of medical sciences : MJMS · 2020Review
- Brother-brother or father-son? How a dropout of AmelX may facilitate the elucidation of a familial relationship.International journal of legal medicine · 2020Article
- Identification of human remains using Rapid DNA analysis.International journal of legal medicine · 2020Article
Corrections and comments
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Authors and funding
7 authors at 4 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
This review presents the basic problems and currently available molecular techniques used for genetic profiling in disaster victim identification (DVI). The environmental conditions of a mass disaster often result in severe fragmentation, decomposition and intermixing of the remains of victims. In such cases, traditional identification based on the anthropological and physical characteristics of the victims is frequently inconclusive. This is the reason why DNA profiling became the gold standard for victim identification in mass-casualty incidents (MCIs) or any forensic cases where human remains are highly fragmented and/or degraded beyond recognition. The review provides general information about the sources of genetic material for DNA profiling, the genetic markers routinely used during genetic profiling (STR markers, mtDNA and single-nucleotide polymorphisms [SNP]) and the basic statistical approaches used in DNA-based disaster victim identification. Automated technological platforms that allow the simultaneous analysis of a multitude of genetic markers used in genetic identification (oligonucleotide microarray techniques and next-generation sequencing) are also presented. Forensic and population databases containing information on human variability, routinely used for statistical analyses, are discussed. The final part of this review is focused on recent developments, which offer particularly promising tools for forensic applications (mRNA analysis, transcriptome variation in individuals/populations and genetic profiling of specific cells separated from mixtures).
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.