ReviewCurrent opinion in neurology2011
Personality and social cognition in neurodegenerative disease.
Review in Current opinion in neurology, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 39 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
39 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Awareness impairment in Alzheimer's disease and frontotemporal dementia: a systematic MRI review.Journal of neurology · 2023Pooled it
- Unveiling discrepancies in depression detection among persons with dementia: A comparative analysis of caregiver and self-report.Journal of Alzheimer's disease : JAD · 2026Article
- Neurodegeneration and Homelessness: A Bidirectional Relationship Shaping Health and Vulnerability.The Yale journal of biology and medicine · 2026Review
- Non-fluent agrammatic variant of primary progressive aphasia in a bilingual Mandarin/English speaker: a case report.Archives of clinical neuropsychology : the official journal of the National Academy of Neuropsychologists · 2026Article
- Emotional recognition technologies applied to health: review and challenges.Revista brasileira de psiquiatria (Sao Paulo, Brazil : 1999) · 2025Review
- Comprehension of acoustically degraded emotional prosody in Alzheimer's disease and primary progressive aphasia.Scientific reports · 2024Article
- Personality and neuropsychiatric symptoms in individuals diagnosed with long COVID.BMC infectious diseases · 2024Article
- Neuroprotective Potential of Pyranocoumarins fromAntioxidants (Basel, Switzerland) · 2023Article
- Impaired Knowledge of Social Norms in Dementia and Psychiatric Disorders: Validation of the Social Norms Questionnaire-Dutch Version (SNQ-NL).Assessment · 2022Article
- Integrated Approaches to Identify miRNA Biomarkers Associated with Cognitive Dysfunction in Multiple Sclerosis Using Text Mining, Gene Expression, Pathways, and GWAS.Diagnostics (Basel, Switzerland) · 2022Article
- Multimodal mechanisms of human socially reinforced learning across neurodegenerative diseases.Brain : a journal of neurology · 2022Article
- Using a Computer-Based Virtual Environment to Assess Social Cognition in Aging: An Exploratory Study of the REALSoCog Task.Frontiers in psychology · 2022Article
- Socio-emotional and motor engagement during musical activities in older adults with major neurocognitive impairment.Scientific reports · 2021Article
- Social cognition and social functioning in patients with amnestic mild cognitive impairment or Alzheimer's dementia.Journal of neuropsychology · 2021Article
- Interoception Primes Emotional Processing: Multimodal Evidence from Neurodegeneration.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2021Article
- Salience driven attention is pivotal to understanding others' intentions.Cognitive neuropsychology · 2021Article
- Facial expressiveness and physiological arousal in frontotemporal dementia: Phenotypic clinical profiles and neural correlates.Cognitive, affective & behavioral neuroscience · 2019Article
- Neurocognitive mechanisms of theory of mind impairment in neurodegeneration: a transdiagnostic approach.Neuropsychiatric disease and treatment · 2019Review
- Association Between Social Cognition Changes and Resting State Functional Connectivity in Frontotemporal Dementia, Alzheimer's Disease, Parkinson's Disease, and Healthy Controls.Frontiers in neuroscience · 2019Article
- Resting parasympathetic dysfunction predicts prosocial helping deficits in behavioral variant frontotemporal dementia.Cortex; a journal devoted to the study of the nervous system and behavior · 2018Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
Abstract
purpose of reviewNeurodegenerative diseases often cause focal damage to brain structures mediating social cognition and personality, resulting in altered interpersonal communication and behavior. We review recent research describing this phenomenon in various aspects of social cognition. RECENT
findingsCorresponding to their pervasive socioemotional deficits, patients with frontotemporal dementia perform poorly on laboratory-based tasks including recognizing emotions, attending to salient information that guides social behavior, representing social knowledge, comprehending others' mental states, and maintaining insight to their own difficulties. Together with poor executive and regulation mechanisms, these social cognition deficits ultimately impact behavior. Patients with logopenic and nonfluent primary progressive aphasia have some deficits recognizing emotional prosody, whereas those with the semantic variant show more widespread deficits in social comprehension. Although Alzheimer's disease patients perform poorly on some social cognition tasks, this typically reflects general cognitive impairment, and their real-life social functioning is less affected than in diseases targeting frontotemporal structures. Studies in motor diseases such as Parkinson's suggest some degradation of emotion recognition and social comprehension, which should be investigated further. SUMMARY: We summarize recent findings concerning perception and evaluation of socioemotional information, social knowledge storage and access, advanced information processing mechanisms, and behavioral response selection and regulation across various neurodegenerative diseases.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.