Evidence map›Paper›PMID 22000352›Full record

ArticleEmerging infectious diseases2011

Multidrug-resistant tuberculosis, People's Republic of China, 2007-2009.

Guang Xue He, Hai Ying Wang, Martien W Borgdorff, Dick van Soolingen, Marieke J van der Werf, Zhi Min Liu, Xue Zheng Li, Hui Guo, Yan Lin Zhao, Jay K Varma and 2 more

Abstract readMulticenter Study
In one paragraph

Article in Emerging infectious diseases, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 2 syntheses or guidelines pooled it.

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  17. Transmission of Mycobacterium tuberculosis in China: a population-based molecular epidemiologic study.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2015
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Guang Xue HeChinese Center for Disease Control and Prevention, Beijing, People's Republic of China. heguangxue@chinatb.org
Hai Ying Wang
Martien W Borgdorff
Dick van Soolingen
Marieke J van der Werf
Zhi Min Liu
Xue Zheng Li
Hui Guo
Yan Lin Zhao
Jay K Varma
Christopher P Tostado
Susan van den Hof

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We conducted a case-control study to investigate risk factors for multidrug-resistant tuberculosis (MDR TB) in the People's Republic of China. Genotyping analysis was used to estimate the percentage of cases from recent transmission among 100 MDR TB case-patients hospitalized during April 2007-July 2009. Molecular subtyping of isolates showed that 41% of MDR TB strains clustered. Beijing genotype was found in 94% of the MDR TB isolates and 79% of the pan-susceptible isolates. In multivariate analysis, MDR TB was independently associated with Beijing genotype, retreatment for TB, symptoms lasting >3 months before first evaluation at the hospital, lack of health insurance, and being a farmer (vs. being a student). MDR TB was associated with Beijing genotype and lower socioeconomic status. A large percentage of MDR TB cases seemed to result from recent transmission. Early detection, effective treatment, and infection control measures for MDR TB are needed to reduce transmission.

Indexed as

AdultAntibiotics, AntitubercularBacterial Typing TechniquesCase-Control StudiesChinaFemaleGenotypeHumansMaleMicrobial Sensitivity TestsMiddle AgedMycobacterium tuberculosisPhylogenyRisk FactorsTuberculosis, Multidrug-ResistantAntibiotics, Antitubercular

Identifiers

PMID22000352
PMCPMC3310678

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.