Evidence map›Paper›PMID 22000008›Full record

ReviewCell2011

Hiding in plain sight: how HIV evades innate immune responses.

Nicolas Manel, Dan R Littman

Abstract readReview
In one paragraph

Review in Cell, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 37 papers.

0numbers the graph read from it
0cells of the map it votes in
37citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

37 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Review
  6. μ-Lat: A mouse model to evaluate human immunodeficiency virus eradication strategies.FASEB journal : official publication of the Federation of American Societies for Experimental Biology · 2020
    Article
  7. Review
  8. Article
  9. Review
  10. Article
  11. Article
  12. HIV-1 and interferons: who's interfering with whom?Nature reviews. Microbiology · 2015
    Review
  13. Article
  14. Article
  15. Article
  16. Mouse knockout models for HIV-1 restriction factors.Cellular and molecular life sciences : CMLS · 2014
    Review
  17. Article
  18. Small molecule inhibition of SAMHD1 dNTPase by tetramer destabilization.Journal of the American Chemical Society · 2014
    Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Nicolas ManelInstitut Curie-INSERM U, Paris, France. nicolas.manel@curie.fr
Dan R Littman

Funding

Dendritic Cell Restriction and Innate Immune Sensing of HIV InfectionR21AI084633 · NIAID · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI LITTMAN, DAN · 2010 to 2011
$463k
Howard Hughes Medical InstituteNIAID NIH HHS R21 AI084633
6 · The paper itself

Abstract

Two groups have identified SAMHD1, a protein encoded by an Aicardi-Goutières Syndrome susceptibility gene, as the factor that restricts infection of macrophages and dendritic cells with HIV-1. Here we discuss implications of this discovery for induction of antiviral protective immunity.

Indexed as

HIV-1Immune EvasionImmunity, InnateAdaptive ImmunityAIDS VaccinesAutoimmune Diseases of the Nervous SystemDendritic CellsHIV InfectionsHumansMacrophagesNervous System MalformationsAIDS Vaccines

Identifiers

PMID22000008
PMCPMC3624893

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.