ArticleBMC gastroenterology2011
Risk factors associated with symptomatic cholelithiasis in Taiwan: a population-based study.
Article in BMC gastroenterology, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 39 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
39 citing papers in PubMed, 79 citations in OpenAlex.
- A retrospective observational study: are gallstone patients aging, or are the elderly more susceptible to gallstones?BMC gastroenterology · 2026Observational
- Observational
- Unlocking the self-care program for cholecystectomy patients from global imperatives for quality of life (QoL) and prevention of postoperative complications.Przeglad gastroenterologiczny · 2026Article
- Impact of Systemic Lupus Erythematosus (SLE) on Short-Term Outcomes of Cholecystectomy for Acute Cholecystitis: An Analysis of the US National Readmission Database, 2016-2020.Journal of hepato-biliary-pancreatic sciences · 2025Article
- Causal associations between changes in lipid profiles and risk of gallstone disease: a two-sample Mendelian randomization study.Annals of translational medicine · 2022Article
- Gallstone Is Associated with Metabolic Factors and Exercise in Korea.Healthcare (Basel, Switzerland) · 2022Article
- Risk of gallstones based on ABCG8 rs11887534 single nucleotide polymorphism among Taiwanese men and women.BMC gastroenterology · 2021Article
- Changes in Hematological Parameters and Liver Enzymes During Laparoscopic Cholecystectomy.Cureus · 2021Article
- Serum lipid levels are the risk factors of gallbladder stones: a population-based study in China.Lipids in health and disease · 2020Article
- Association of Body Mass Index and Diet with Symptomatic Gall Stone Disease: A Case-Control Study.Cureus · 2020Article
- Gallstone disease and its correlates among patients attending teaching hospital of North India.Journal of family medicine and primary care · 2019Article
- Association of use of selective serotonin reuptake inhibitors with risk of acute pancreatitis: a case-control study in Taiwan.European journal of clinical pharmacology · 2017Article
- Fluvastatin use and risk of acute pancreatitis: a population-based case-control study in Taiwan.BioMedicine · 2017Article
- Analysis of gallstone disease after gastric cancer surgery.Gastric cancer : official journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association · 2017Article
- Nonalcoholic fatty liver was associated with asymptomatic gallstones in a Chinese population.Medicine · 2017Article
- Correlation between proton pump inhibitors and risk of pyogenic liver abscess.European journal of clinical pharmacology · 2017Article
- Etodolac and the risk of acute pancreatitis.BioMedicine · 2017Article
- Immune thrombocytopenic purpura might be an early hematologic manifestation of undiagnosed human immunodeficiency virus infection.Internal and emergency medicine · 2017Article
- No association between losartan use and acute pancreatitis in hypertensive patients.European journal of hospital pharmacy : science and practice · 2017Article
- Metformin Use Correlates with Reduced Risk of Gallstones in Diabetic Patients: A 12-Year Follow-up Study.Frontiers in pharmacology · 2017Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundCholelithiasis has become a major health problem in Taiwan. The predominant type of gallstone found in Asian populations differs from that in the West, indicating possible differences in the etiology and risk factors for cholelithiasis. The aim of this study is to investigate the risk factors for cholelithiasis using data representative of the general population.
methodsWe performed a population-based, case-control study in which we analyzed medical data for 3725 patients newly diagnosed with cholelithiasis and 11175 gender- and age-matched controls with no history of cholelithiasis, using information obtained from the 2005 Registry for Beneficiaries of the National Health Insurance Research Database. Coexisting medical conditions were included in the analysis. Relative risks were estimated by adjusted odds ratio (OR) and 95% confidence interval (CI) using a multivariate logistic regression analysis.
resultsAfter controlling for the other covariates, multivariate logistic regression analysis identified the following as risk factors for cholelithiasis (in descending order of contribution): Among all patients - hepatitis C (OR = 2.78), cirrhosis (OR = 2.47), hepatitis B (OR = 2.00), obesity (OR = 1.89), and hyperlipidemia (OR = 1.54); Among women - hepatitis C (OR = 3.05), cirrhosis (OR = 1.92), obesity (OR = 1.91), menopause (OR = 1.61), hepatitis B (OR = 1.54), and hyperlipidemia (OR = 1.49). Diabetes mellitus appeared to have a marked influence on the development of cholelithiasis but was not identified as a significant independent risk factor for cholelithiasis.
conclusionsThe risk factors for cholelithiasis were obesity, hyperlipidemia, hepatitis B infection, hepatitis C infection, and cirrhosis in both genders, and menopause in females. Despite differences in the predominate type of gallstone in Asian versus Western populations, we identified no unique risk factors among the population of Taiwan.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.