Trial reportInternational journal of paediatric dentistry2012
Mother and youth access (MAYA) maternal chlorhexidine, counselling and paediatric fluoride varnish randomized clinical trial to prevent early childhood caries.
Trial report in International journal of paediatric dentistry, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT00066950 (Prevention Management Model for Early Childhood Caries), which is not on this map. Cited by 21 papers, 4 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Prevention Management Model for Early Childhood Caries
Who cites it
21 citing papers in PubMed, 4 syntheses or guidelines pooled it, 36 citations in OpenAlex.
- Interventions with pregnant women, new mothers and other primary caregivers for preventing early childhood caries.The Cochrane database of systematic reviews · 2024Pooled it
- Interventions with pregnant women, new mothers and other primary caregivers for preventing early childhood caries.The Cochrane database of systematic reviews · 2019Pooled it
- Fluoride varnishes for preventing dental caries in children and adolescents.The Cochrane database of systematic reviews · 2013Pooled it
- Effect of Antimicrobial Interventions on the Oral Microbiota Associated with Early Childhood Caries.Pediatric dentistryPooled it
- Randomised clinical trial investigating self-assembling peptide PClinical oral investigations · 2020Trial
- Dental attendance among low-income women and their children following a brief motivational counseling intervention: A community randomized trial.Social science & medicine (1982) · 2015Trial
- Examination criteria and calibration procedures for prevention trials of the Early Childhood Caries Collaborating Centers.Journal of public health dentistry · 2015Trial
- Clinically determined and self-reported dental status during and after pregnancy among low-income Hispanic women.Journal of public health dentistry · 2013Trial
- The Evolving Microbiome of Dental Caries.Microorganisms · 2024Review
- The contribution of maternal factors to the oral microbiota of the child: Influence from early life and clinical relevance.The Japanese dental science review · 2023Review
- Oral Health Coaches at Well-Baby Clinics to Promote Oral Health in Preschool Children From the First Erupted Tooth: Protocol for a Multisite, Pragmatic Randomized Controlled Trial.JMIR research protocols · 2022Article
- The effectiveness of a caries preventive program in mothers and infants - An 18- month follow-up study.Journal of dental sciences · 2020Article
- Fluorides and Other Preventive Strategies for Tooth Decay.Dental clinics of North America · 2018Review
- Acculturation and Pediatric Minority Oral Health Interventions.Dental clinics of North America · 2017Review
- Oral microflora in preschool children attending a fluoride varnish program: a cross-sectional study.BMC oral health · 2016Article
- Community-based population-level interventions for promoting child oral health.The Cochrane database of systematic reviews · 2016Review
- Preventing Childhood Caries: A Review of Recent Behavioral Research.Journal of dental research · 2016Review
- Recruitment for health disparities preventive intervention trials: the early childhood caries collaborating centers.Preventing chronic disease · 2014Article
- Maternal oral bacterial levels predict early childhood caries development.Journal of dental research · 2014Observational
- A model for community-based pediatric oral heath: implementation of an infant oral care program.International journal of dentistry · 2014Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors at 3 institutions in 1 country.
Funding
Abstract
backgroundMexican-American children have a higher caries prevalence than the U.S. average. The Mothers and Youth Access (MAYA) study was a randomized clinical trial initiated to address this problem.
aimComparison of the efficacy of two prevention interventions in reducing early childhood caries (ECC).
designAll 361 randomized mother-child dyads received oral health counselling. Beginning at 4 months postpartum, intervention mothers received chlorhexidine (CHX) mouthrinse for 3 months beginning 4 months postpartum and children received fluoride varnish (FV) every 6 months from age 12-36 months. Control group children received FV if precavitated lesions developed. Salivary mutans streptococci (MS) and lactobacilli were assessed.
resultsNo significant difference in children's 36-month caries incidence between groups; 34% in each group developed caries [(d(2+) fs) > 0]. About half of control group developed precavitated lesions and received therapeutic FV. Maternal MS levels declined during CHX use, but increased when discontinued.
conclusionsMaternal postpartum CHX regimen, oral health counselling and preventive child FV applications were not more efficacious than maternal counselling with child therapeutic FV for precavitated lesions for ECC prevention. FV for young children with brief maternal CHX use and oral health counselling may need to be combined with additional or longer-term therapies to significantly reduce ECC in high-risk populations.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.