ArticleThe Journal of infectious diseases2011
Study of a localized meningococcal meningitis epidemic in Burkina Faso: incidence, carriage, and immunity.
Article in The Journal of infectious diseases, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 2 of them syntheses that pooled it.
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17 citing papers in PubMed, 2 syntheses or guidelines pooled it, 31 citations in OpenAlex.
- Meningococcal carriage by age in the African meningitis belt: a systematic review and meta-analysis.Epidemiology and infection · 2019Pooled it
- Pooled it
- Knowledge, beliefs and practices regarding prevention of bacterial meningitis in Burkina Faso, 5 years after MenAfriVac mass campaigns.PloS one · 2021Article
- Narrative review of methods and findings of recent studies on the carriage of meningococci and other Neisseria species in the African Meningitis Belt.Tropical medicine & international health : TM & IH · 2019Review
- Atmospheric Dust, Early Cases, and Localized Meningitis Epidemics in the African Meningitis Belt: An Analysis Using High Spatial Resolution Data.Environmental health perspectives · 2018Article
- The association between respiratory tract infection incidence and localised meningitis epidemics: an analysis of high-resolution surveillance data from Burkina Faso.Scientific reports · 2017Article
- A Seroepidemiological Study of Serogroup A Meningococcal Infection in the African Meningitis Belt.PloS one · 2016Article
- Meningococcal Seroepidemiology 1 Year After the PsA-TT Mass Immunization Campaign in Burkina Faso.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2015Article
- Modeling Long-term Vaccination Strategies With MenAfriVac in the African Meningitis Belt.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2015Article
- The Diversity of Meningococcal Carriage Across the African Meningitis Belt and the Impact of Vaccination With a Group A Meningococcal Conjugate Vaccine.The Journal of infectious diseases · 2015Article
- Response Strategies against Meningitis Epidemics after Elimination of Serogroup A Meningococci, Niger.Emerging infectious diseases · 2015Article
- A multi-state spatio-temporal Markov model for categorized incidence of meningitis in sub-Saharan Africa.Epidemiology and infection · 2013Article
- Seasonality of meningitis in Africa and climate forcing: aerosols stand out.Journal of the Royal Society, Interface · 2013Article
- Knowledge of obstetric fistula prevention amongst young women in urban and rural Burkina Faso: a cross-sectional study.PloS one · 2013Article
- Article
- Definition and characterization of localised meningitis epidemics in Burkina Faso: a longitudinal retrospective study.BMC infectious diseases · 2012Article
- Article
Corrections and comments
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Authors and funding
12 authors at 5 institutions in 4 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundTo better understand localized meningococcal meningitis epidemics, we evaluated a serogroup A (NmA) epidemic in Burkina Faso by surveillance, carriage, and seroprevalence studies.
methodsDuring March-April 2006, cerebrospinal fluid samples from patients suspected to have meningitis in 3 epidemic villages were analyzed by culture or polymerase chain reaction. We assessed meningococcal carriage and serogroup-specific serum bactericidal antibody titers with baby rabbit complement (rSBA) in a representative population sample (N = 624; age range, 1-39 years). A serogroup A/C polysaccharide vaccine campaign occurred in parallel.
resultsCumulative incidence of Nm meningitis was 0.45% and varied among villages (0.08%-0.91%). NmA carriage prevalence was 16% without variation by vaccination status. NmA carriage and anti-NmA seroprevalence varied by village and incidence. In the 2 villages with highest incidence and seroprevalence, presence of rSBA titers ≥8 was associated with NmA carriage (odds ratio [OR], 9.33 [95% confidence interval {CI}, 1.90-45.91]) and vaccination ≤4 days earlier (OR, 0.10 [95% CI, .03-.32]). Visibly purulent or Nm meningitis was significantly associated with recent flulike symptoms and exposure to kitchen smoke (risk ratios >15).
conclusionsA surge of NmA carriage may be involved in the development of meningococcal epidemics and rapidly increase anti-NmA seroprevalence. Flulike infection and kitchen smoke may contribute to the strength of epidemics.
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