ArticleJournal of clinical microbiology2011
Age- and gender-associated Staphylococcus aureus spa types found among nasal carriers in a general population: the Tromso Staph and Skin Study.
Article in Journal of clinical microbiology, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 49 papers.
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Who cites it
49 citing papers in PubMed.
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- Long-term trends in incidence and mortality in Staphylococcus aureus bacteraemia; a retrospective population-based study from Central Norway 1996-2022.BMC infectious diseases · 2026Article
- NasalInternational journal of molecular sciences · 2026Article
- Occurrence, variability and evolutionary relations of efflux pump determinants across five pathogenicFrontiers in pharmacology · 2026Article
- Sex-Specific Associations Between Smokeless Tobacco Use andTobacco use insights · 2026Article
- Prevalence and Diversity ofAnimals : an open access journal from MDPI · 2025Article
- Identification of NovelInternational journal of molecular sciences · 2025Article
- OralPathogens (Basel, Switzerland) · 2024Article
- Nasal Staphylococcus aureus Carriage and Antimicrobial Resistance Profiles Among Community-Dwelling Adults in Jiangsu, China.Infectious diseases and therapy · 2024Article
- MIC distribution analysis identifies differences in AMR between population sub-groups.Wellcome open research · 2024Article
- Co-culturing withFrontiers in cellular and infection microbiology · 2024Article
- Exploring differentially expressed genes of Staphylococcus aureus exposed to human tonsillar cells using RNA sequencing.BMC microbiology · 2023Article
- Molecular and Source-Specific Profiling of HospitalMicroorganisms · 2023Article
- Toxin exposure and HLA alleles determine serum antibody binding to toxic shock syndrome toxin 1 (TSST-1) ofFrontiers in immunology · 2023Article
- Circulating sex-steroids andEpidemiology and infection · 2022Article
- Characterising clinical Staphylococcus aureus isolates from the sinuses of patients with chronic rhinosinusitis.Scientific reports · 2021Article
- Shotgun-metagenomics based prediction of antibiotic resistance and virulence determinants in Staphylococcus aureus from periprosthetic tissue on blood culture bottles.Scientific reports · 2021Article
- SaQuant: a real-time PCR assay for quantitative assessment of Staphylococcus aureus.BMC microbiology · 2021Article
- Methicillin resistant staphylococci isolated in clinical samples: a 3-year retrospective study analysis.Future science OA · 2021Article
- Circulating sex-steroids and Staphylococcus aureus nasal carriage in a general female population.European journal of endocrinology · 2021Article
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6 authors.
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Abstract
Staphylococcus aureus nasal carriers risk autoinfection; however, knowledge about the factors that make specific strains successful colonizers is limited. This study was undertaken to identify the most successful S. aureus clones in nasal carriers and compare their distribution among host groups. The population structure of S. aureus isolates from healthy adults was investigated by spa typing 1,981 isolates from persistent and intermittent nasal carriers participating in a health survey. In the baseline screening (1,113 isolates), the most common spa types were t012 (8.4%), t084 (7.6%), and t065 (4.9%). Three large spa clonal complexes (spa CC012, spa CC065, and spa CC084) comprised 62.4% of the isolates. In multivariate models adjusted for age and smoking status, male sex was associated with higher risk for spa type t084 (odds ratio [OR], 1.72; 95% confidence interval [CI], 1.06 to 2.77), and lower risk of spa type t012 (OR, 0.60; 95% CI, 0.39 to 0.92) colonization. The prevalence of spa type t012 decreased significantly with increasing age (P = 0.03), with a prevalence almost twice as high in the youngest group (age 30 to 44 years, prevalence = 11.1%) as in the oldest group (age, 60 to 87 years; prevalence = 5.6%). Among baseline isolates, spa type t084 had a twofold-higher prevalence among intermittent carriers than among persistent carriers (10.6% versus 5.5%; P = 0.04). In summary, the two most prevalent spa types found in this study were significantly associated with age and/or gender. This may provide valuable clues to the multifactorial mechanisms, among them bacterial factors, involved in nasal colonization with S. aureus.
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