ArticleJournal of clinical microbiology2011
Comparative performance of human papillomavirus DNA testing using novel sample collection methods.
Article in Journal of clinical microbiology, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
14 citing papers in PubMed, 1 synthesis or guideline pooled it, 31 citations in OpenAlex.
- Concordance of Primary Human Papillomavirus Testing Among Clinicians and Patients: A Systematic Review.Journal of women's health (2002) · 2023Pooled it
- Clinical performance of the Roche Cobas 4800 HPV test for primary cervical cancer screening in a Chinese population.PloS one · 2022Article
- Universal cervical cancer control through a right to health lens: refocusing national policy and programmes on underserved women.BMC international health and human rights · 2020Article
- Self-Collected Specimens Revealed a Higher Vaccine- and Non-Vaccine-Type Human Papillomavirus Prevalences in a Cross-Sectional Study in Akuse.Advances in preventive medicine · 2020Article
- Feasibility, validity and acceptability of self-collected samples for human papillomavirus (HPV) testing in rural Malawi.Malawi medical journal : the journal of Medical Association of Malawi · 2018Article
- Prevalence of Human Papillomavirus Infection and Cervical Cancer Screening among Riverside Women of the Brazilian Amazon.Revista brasileira de ginecologia e obstetricia : revista da Federacao Brasileira das Sociedades de Ginecologia e Obstetricia · 2017Article
- Differences in age-specific HPV prevalence between self-collected and health personnel collected specimen in a cross-sectional study in Ghana.Infectious agents and cancer · 2017Article
- Human Papillomavirus Infection in Women Who Submit Self-collected Vaginal Swabs After Internet Recruitment.Journal of community health · 2015Article
- Association of Chlamydia trachomatis infection with redetection of human papillomavirus after apparent clearance.The Journal of infectious diseases · 2013Article
- Association of HPV types 6, 11, 16, and 18 DNA detection and serological response in unvaccinated adolescent women.Journal of medical virology · 2013Article
- Can clinical tests help monitor human papillomavirus vaccine impact?International journal of cancer · 2013Article
- Differences in patterns of high-risk human papillomavirus infection between urban and rural low-resource settings: cross-sectional findings from Mali.BMC women's health · 2013Article
- Human papillomavirus genotypes detected in clinician-collected and self-collected specimens from women living in the Mississippi Delta.BMC infectious diseases · 2013Article
- Acceptability and usability of self-collected sampling for HPV testing among African-American women living in the Mississippi Delta.Women's health issues : official publication of the Jacobs Institute of Women's HealthArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors at 5 institutions in 1 country.
Funding
Abstract
To explore alternative cervical cancer screening approaches in an underserved population, we compared the performance of human papillomavirus (HPV) DNA assays in combination with different sample collection methods for primary cervical screening in the Mississippi Delta region. Three specimens were collected from women aged 26 to 65 years who were either routinely undergoing screening (n = 252) or not (n = 191): clinician-collected cervical specimens, clinician-collected cervicovaginal specimens, and self-collected cervicovaginal specimens taken at home. A novel collection device and medium were used for cervicovaginal sampling. Specimens were tested by three HPV DNA assays: hybrid capture 2 (HC2; Qiagen Corp., Gaithersburg, MD), Linear Array (LA; Roche Molecular Systems, Pleasanton, CA), and Amplicor (Roche Molecular Systems, Pleasanton, CA). Liquid-based cytology was performed on cervical specimens. We compared the overall positivity (a proxy for clinical specificity) for any carcinogenic HPV genotype and calculated the agreement across assay and specimen type using McNemar's test for differences in test positivity. Across all three assays there were no significant differences between clinician-collected and self-collected cervicovaginal specimens (P > 0.01 for all comparisons). For both cervicovaginal specimens (clinician collected and self-collected), fewer women tested positive by HC2 than by LA or Amplicor (P < 0.01 for all comparisons). HC2 had the best agreement between specimens for all assays. HC2 is likely more clinically specific, although possibly less sensitive, than either PCR test. Thus, use of HC2 on cervicovaginal specimens for screening could result in fewer referrals compared to LA and Amplicor.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.