ArticleJournal of clinical microbiology2011
Five-year outbreak of community- and hospital-acquired Mycobacterium porcinum infections related to public water supplies.
Article in Journal of clinical microbiology, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.
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Who cites it
26 citing papers in PubMed, 75 citations in OpenAlex.
- Clonal spread of Mycobacterium monacense strains among patients with extrapulmonary mycobacteriosis.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2026Article
- A Case Report of Wound Infection Caused byInfection and drug resistance · 2025Article
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- Sources, transmission and hospital-associated outbreaks of nontuberculous mycobacteria: a review.Future microbiology · 2024Review
- Antimicrobial Resistance in Rapidly Growing Nontuberculous Mycobacteria among Domestic and Wild Animals Emphasizing the Zoonotic Potential.Microorganisms · 2023Article
- Surgical site infections by atypical mycobacteria: prevalence and species characterization using MALDI-TOF and molecular LCD chip array.Infection · 2022Article
- Drinking natural water unchangeably is associated with reduced all-cause mortality in elderly people: A longitudinal prospective study from China.Frontiers in public health · 2022Article
- Understanding building-occupant-microbiome interactions toward healthy built environments: A review.Frontiers of environmental science & engineering · 2021Review
- The Many Hosts of Mycobacteria 8 (MHM8): A conference report.Tuberculosis (Edinburgh, Scotland) · 2020Review
- Article
- Notes from the Field: Hospital Water Contamination Associated with a Pseudo-Outbreak of Mycobacterium porcinum - Wisconsin, 2016-2018.MMWR. Morbidity and mortality weekly report · 2019Article
- Revisiting John Snow to Meet the Challenge of Nontuberculous Mycobacterial Lung Disease.International journal of environmental research and public health · 2019Review
- Historical evolution of the diseases caused by non-pigmented rapidly growing mycobacteria in a University Hospital.Revista espanola de quimioterapia : publicacion oficial de la Sociedad Espanola de Quimioterapia · 2019Article
- Article
- A Pure Life: The Microbial Ecology of High Purity Industrial Waters.Microbial ecology · 2018Review
- Draft Genome Sequence of Mycobacterium porcinum CSURP1564.Genome announcements · 2018Article
- Global Environmental Nontuberculous Mycobacteria and Their Contemporaneous Man-Made and Natural Niches.Frontiers in microbiology · 2018Review
- Environmental Nontuberculous Mycobacteria in the Hawaiian Islands.PLoS neglected tropical diseases · 2016Article
- A neonate born with Mycobacterium cosmeticum bacteraemia.BMJ case reports · 2015Article
- Epidemiology of Nontuberculous Mycobacteria in French Polynesia.Journal of clinical microbiology · 2015Article
Corrections and comments
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Authors and funding
10 authors at 4 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Mycobacterium porcinum is a rarely encountered rapidly growing Mycobacterium (RGM). We identified M. porcinum from 24 patients at a Galveston university hospital (University of Texas Medical Branch) over a 5-year period. M. porcinum was considered a pathogen in 11 (46%) of 24 infected patients, including 4 patients with community-acquired disease. Retrospective patient data were collected, and water samples were cultured. Molecular analysis of water isolates, clustered clinical isolates, and 15 unrelated control strains of M. porcinum was performed. Among samples of hospital ice and tap water, 63% were positive for RGM, 50% of which were M. porcinum. Among samples of water from the city of Galveston, four of five households (80%) were positive for M. porcinum. By pulsed-field gel electrophoresis (PFGE), 8 of 10 environmental M. porcinum were determined to belong to two closely related clones. A total of 26 of 29 clinical isolates subjected to PFGE (including isolates from all positive patients) were clonal with the water patterns, including patients with community-acquired disease. Fifteen control strains of M. porcinum had unique profiles. Sequencing of hsp65, recA, and rpoB revealed the PFGE outbreak clones to have identical sequences, while unrelated strains exhibited multiple sequence variants. M. porcinum from 22 (92%) of 24 patients were clonal, matched hospital- and household water-acquired isolates, and differed from epidemiologically unrelated strains. M. porcinum can be a drinking water contaminant, serve as a long-term reservoir (years) for patient contamination (especially sputum), and be a source of clinical disease. This study expands concern about public health issues regarding nontuberculous mycobacteria. Multilocus gene sequencing helped define clonal populations.
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