ArticleGenesis (New York, N.Y. : 2000)2012
Pangolin expression influences the development of a morphological novelty: beetle horns.
Article in Genesis (New York, N.Y. : 2000), 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
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Who cites it
6 citing papers in PubMed.
- From Egg to Adult: A Developmental Table of the Ant Monomorium pharaonis.Journal of experimental zoology. Part B, Molecular and developmental evolution · 2024Article
- Spatial and temporal regulation of Wnt signaling pathway members in the development of butterfly wing patterns.Science advances · 2023Article
- Notch signaling patterns head horn shape in the bull-headed dung beetle Onthophagus taurus.Development genes and evolution · 2020Article
- Article
- Insights into the development and evolution of exaggerated traits using de novo transcriptomes of two species of horned scarab beetles.PloS one · 2014Article
- Beetle horns and horned beetles: emerging models in developmental evolution and ecology.Wiley interdisciplinary reviews. Developmental biologyReview
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2 authors.
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Abstract
Morphological diversity arises during development through the actions and interactions of diverse developmental pathways. Among those, the Wnt pathway is known to contribute to diverse developmental processes such as segmentation and the morphogenesis of appendages. Here, we characterize a transcription factor in the Wnt pathway, pangolin (pan), to investigate the role of Wnt signaling in the development of evolutionarily novel body structures: the horns of beetles. Beetle horns are highly diverse in size, shape, and number and develop principally from two major body regions: the head and prothorax. We investigate horns in two species of the genus Onthophagus using comparative in situ hybridization, larval RNA interference, and allometric measurements to analyze whether horn formation is regulated by pan and by extension the Wnt pathway. Our results illustrate that pan expression affects beetle horn growth in a species-, sex-, and location-specific manner in two morphologically distinct, yet closely-related, Onthophagus species.
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