Evidence map›Paper›PMID 21997831›Full record

ArticleProteins2011

Critical assessment of methods of protein structure prediction (CASP)--round IX.

John Moult, Krzysztof Fidelis, Andriy Kryshtafovych, Anna Tramontano

Abstract read
In one paragraph

Article in Proteins, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 101 papers.

0numbers the graph read from it
0cells of the map it votes in
101citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

101 citing papers in PubMed.

  1. Article
  2. Mass Spectrometry- and Structural Biology-Based Investigation of Proteins.Advances in experimental medicine and biology · 2026
    Review
  3. Petabase-Scale Homology Search for Structure Prediction.Cold Spring Harbor perspectives in biology · 2024
    Review
  4. Article
  5. Petascale Homology Search for Structure Prediction.bioRxiv : the preprint server for biology · 2023
    Article
  6. Illuminating the "Twilight Zone": Advances in Difficult Protein Modeling.Methods in molecular biology (Clifton, N.J.) · 2023
    Article
  7. Where to From Here?Frontiers in molecular biosciences · 2022
    Article
  8. An Overview of Alphafold's Breakthrough.Frontiers in artificial intelligence · 2022
    Review
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Conservation of binding properties in protein models.Computational and structural biotechnology journal · 2021
    Article
  15. Review
  16. Article
  17. Article
  18. Article
  19. Article
  20. Article

41 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

John MoultInstitute for Bioscience and Biotechnology Research, and Department of Cell Biology and Molecular Genetics, University of Maryland, Rockville, MD 20850, USA. jmoult@umd.edu
Krzysztof Fidelis
Andriy Kryshtafovych
Anna Tramontano

Funding

Prospective analysis to determine model accuracy performance and boundaries in the post-AlphaFold2 environmentR01GM100482 · NIGMS · UNIVERSITY OF CALIFORNIA AT DAVIS · PI FIDELIS, KRZYSZTOF A · 2012 to 2025
$11.1M
Platform for Physics-Based Methods in CASP (Comp. Rev. to LM007085)P41LM007085 · NLM · UNIVERSITY OF CALIFORNIA DAVIS · PI FIDELIS, KRZYSZTOF A · 2001 to 2011
$6.5M
CASP6-CASP8 meetingsR13GM072354 · NIGMS · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI ROST, BURKHARD · 2004 to 2008
$194k
NIGMS NIH HHS GM072354NIGMS NIH HHS R01 GM100482NIGMS NIH HHS R13 GM072354NLM NIH HHS LM07085NLM NIH HHS P41 LM007085
6 · The paper itself

Abstract

This article is an introduction to the special issue of the journal PROTEINS, dedicated to the ninth Critical Assessment of Structure Prediction (CASP) experiment to assess the state of the art in protein structure modeling. The article describes the conduct of the experiment, the categories of prediction included, and outlines the evaluation and assessment procedures. Methods for modeling protein structure continue to advance, although at a more modest pace than in the early CASP experiments. CASP developments of note are indications of improvement in model accuracy for some classes of target, an improved ability to choose the most accurate of a set of generated models, and evidence of improvement in accuracy for short "new fold" models. In addition, a new analysis of regions of models not derivable from the most obvious template structure has revealed better performance than expected.

Indexed as

Models, MolecularComputational BiologyProtein ConformationProteinsProteins

Identifiers

PMID21997831
PMCPMC4180088

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.