ArticleThe American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry2012
Course of depression and mortality among older primary care patients.
Article in The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04948996 (Effectiveness of Group Versus Individual Self-management of Depression Using a Mobile App to Increase Treatment Adherence Among Users of a University-based Helpline in the Dominican Republic.), which is not on this map. Cited by 15 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Effectiveness of Group Versus Individual Self-management of Depression Using a Mobile App to Increase Treatment Adherence Among Users of a University-based Helpline in the Dominican Republic.
Who cites it
15 citing papers in PubMed.
- Are Big Five personality traits associated with trajectories of depressive symptom among middle-aged and older adults in China?Social psychiatry and psychiatric epidemiology · 2026Article
- Relationship Between Sarcopenia and the Trajectories of Depressive Symptoms Among Chinese Older Adults: The Mediating Effect of Social Participation.International journal of behavioral medicine · 2026Article
- Trajectories of depressive symptoms and risk of chronic liver disease: evidence from CHARLS.BMC gastroenterology · 2025Article
- Using machine learning to predict the probability of incident 2-year depression in older adults with chronic diseases: a retrospective cohort study.BMC psychiatry · 2024Article
- The depressed frail phenotype as a risk factor for mortality in older adults: A prospective cohort in Peru.Heliyon · 2022Article
- Prevalence of loneliness and association with depressive and anxiety symptoms among retirees in Northcentral Nigeria: a cross-sectional study.BMC geriatrics · 2020Article
- Own and partner pain intensity in older couples: longitudinal effects on depressive symptoms.Pain · 2017Article
- Association of detected depression and undetected depressive symptoms with long-term mortality in a cohort of institutionalised older people.Epidemiology and psychiatric sciences · 2017Article
- The Depressed Frail Phenotype: The Clinical Manifestation of Increased Biological Aging.The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry · 2016Review
- Heterogeneity in the three-year course of major depression among older adults.International journal of geriatric psychiatry · 2016Article
- Effects of change in arthritis severity on spouse well-being: The moderating role of relationship closeness.Journal of family psychology : JFP : journal of the Division of Family Psychology of the American Psychological Association (Division 43) · 2015Article
- Socioeconomic and psychosocial adversity in midlife and depressive symptoms post retirement: a 21-year follow-up of the Whitehall II study.The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry · 2015Article
- Prevalence and predictors of persistent versus remitting mood, anxiety, and substance disorders in a national sample of older adults.The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry · 2014Article
- The economic, public health, and caregiver burden of late-life depression.The Psychiatric clinics of North America · 2013Review
- Depression and associated factors in older adults in South Africa.Global health action · 2013Article
Corrections and comments
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Authors and funding
5 authors.
Funding
Abstract
context: Depression is a treatable illness that disproportionately places older adults at increased risk for mortality.
objective: We sought to examine whether there are patterns of course of depression severity among older primary care patients that are associated with increased risk for mortality. DESIGN AND
setting: Our study was a secondary analysis of data from a practice-based randomized controlled trial within 20 primary care practices located in greater New York City, Philadelphia, and Pittsburgh.
participants: The study sample consisted of 599 adults aged 60 years and older recruited from primary care settings. Participants were identified though a two-stage, age-stratified (60-74 years; older than 75 years) depression screening of randomly sampled patients. Severity of depression was assessed using the 24-item Hamilton Depression Rating Scale (HDRS). MEASUREMENTS: : Longitudinal analysis via growth curve mixture modeling was carried out to classify patterns of course of depression severity across 12 months. Vital status at 5 years was ascertained via the National Death Index Plus.
results: Three patterns of change in course of depression severity over 12 months were identified: 1) persistent depressive symptoms, 2) high but declining depressive symptoms, 3) low and declining depressive symptoms. After a median follow-up of 52.0 months, 114 patients had died. Patients with persistent depressive symptoms were more likely to have died compared with patients with a course of high but declining depressive symptoms (adjusted hazard ratio 2.32, 95% confidence interval [1.15-4.69]).
conclusions: Persistent depressive symptoms signaled increased risk of dying in older primary care patients, even after adjustment for potentially influential characteristics such as age, smoking status, and medical comorbidity.
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