Evidence map›Paper›PMID 21997497›Full record

ArticleMenopause (New York, N.Y.)2012

Self-reported estrogen use and newly incident urinary incontinence among postmenopausal community-dwelling women.

Gina M Northington, Heather F de Vries, Hillary R Bogner

Abstract read
In one paragraph

Article in Menopause (New York, N.Y.), 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
1.5field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 10 citations in OpenAlex.

  1. Estrogen inhibits vaginal tropoelastin and TGF-β1 production.International urogynecology journal · 2012
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Gina M NorthingtonDepartment of Obstetrics and Gynecology, University of Pennsylvania, Philadelphia, PA 19104, USA.
Heather F de Vries
Hillary R Bogner
University of Pennsylvania · USCenter for Clinical Research (United States) · US

Funding

REPRODUCTIVE SCIENTIST TRAINING PROGRAMK12HD000849 · NICHD · WASHINGTON UNIVERSITY · PI Danny J Schust · 1988 to 2026
$33.2M
PENN RCMARP30AG031043 · NIA · UNIVERSITY OF PENNSYLVANIA · PI SHEA, JUDY A. · 2007 to 2011
$3.3M
Evolution of Psychopathology in the PopulationR01DA026652 · NIDA · JOHNS HOPKINS UNIVERSITY · PI EATON, WILLIAM W · 2009 to 2013
$2.4M
The Effects of Bipolar Disorder and its Comorbidities on Cognition in Older AdultR01MH084921 · NIMH · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI GILDENGERS, ARIEL GERARD · 2010 to 2014
$1.8M
Course and risk factors for depression in late lifeR01MH082799 · NIMH · UNIVERSITY OF PENNSYLVANIA · PI BOGNER, HILLARY R · 2009 to 2010
$798k
Adherence to Antidepressant Medication and Hypertension TreatmentR34MH085880 · NIMH · UNIVERSITY OF PENNSYLVANIA · PI BOGNER, HILLARY R · 2010 to 2012
$714k
NIA NIH HHS 1P30AG031043-01NIA NIH HHS P30 AG031043NICHD NIH HHS K12 HD000849NICHD NIH HHS K12-HD-000849-21NIDA NIH HHS DA026652NIDA NIH HHS R01 DA026652NIMH NIH HHS MH082799NIMH NIH HHS MH085880NIMH NIH HHS R01 MH082799NIMH NIH HHS R01 MH084921NIMH NIH HHS R34 MH085880
6 · The paper itself

Abstract

objectiveThe aim of this study was to examine the relationship between self-reported estrogen use and newly incident urinary incontinence (UI) among community-dwelling postmenopausal women.

methodsThe study was a population-based longitudinal survey of postmenopausal women who did not report UI in 1993 and for whom complete data were available. Women were classified as having newly incident UI if they reported uncontrolled urine loss within 12 months of the 2004 interview. Condition-specific functional loss secondary to UI was assessed using questions on the participants' inability to engage in certain activities because of UI. The duration of hormone therapy containing estrogen was obtained in 1993 using a structured questionnaire.

resultsAmong the 167 postmenopausal women who did not report UI in 1993, 47 (28.1%) reported newly incident UI, and 31 (18.6%) reported newly incident UI with condition-specific functional loss in 2004. Of the 167 postmenopausal women, 46 (27.5%) reported using hormone therapy containing estrogen ever, and 14 (8.3%) women reported using hormone therapy containing estrogen for 5 years or more in 1993. Estrogen use for 5 years or more was significantly associated with newly incident UI with condition-specific functional loss compared with estrogen use for less than 5 years or having no reported history of estrogen (adjusted relative odds, 3.97; 95% CI, 1.02-15.43) in multivariate models controlling for potentially influential characteristics.

conclusionsPostmenopausal community-dwelling women with a history of estrogen use for 5 years or more were more likely to report newly incident UI with condition-specific functional loss after 10 years of follow-up.

Indexed as

Self ReportAdultAgedEstrogen Replacement TherapyFemaleHumansLongitudinal StudiesMiddle AgedPostmenopauseResidence CharacteristicsSurveys and QuestionnairesUrinary Incontinence

Identifiers

PMID21997497
PMCPMC3262073
OpenAlexW2075257960

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.