ReviewCellular and molecular life sciences : CMLS2012
Acoustic sensors as a biophysical tool for probing cell attachment and cell/surface interactions.
Review in Cellular and molecular life sciences : CMLS, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.
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Who cites it
24 citing papers in PubMed, 115 citations in OpenAlex.
- Preliminary Study on Sensor-Based Detection of an Adherent Cell's Pre-Detachment Moment in a MPWM Microfluidic Extraction System.Sensors (Basel, Switzerland) · 2025Article
- The Recent Development of Acoustic Sensors as Effective Chemical Detecting Tools for Biological Cells and Their Bioactivities.Molecules (Basel, Switzerland) · 2023Review
- Monitoring Cell Adhesion on Polycaprolactone-Chitosan Films with Varying Blend Ratios by Quartz Crystal Microbalance with Dissipation.ACS omega · 2023Article
- Practical Use of Quartz Crystal Microbalance Monitoring in Cartilage Tissue Engineering.Journal of functional biomaterials · 2022Review
- Changes of Viscoelastic Properties of Aptamer-Based Sensing Layers Following Interaction withSensors (Basel, Switzerland) · 2021Article
- Advances in Electrochemical and Acoustic Aptamer-Based Biosensors and Immunosensors in Diagnostics of Leukemia.Biosensors · 2021Review
- Simulation of SAW Sensors with Various Distributed Mass Loadings Using Two-Dimensional Coupling-of-Modes Theory.Sensors (Basel, Switzerland) · 2020Article
- Advances in Analysis of Milk Proteases Activity at Surfaces and in a Volume by Acoustic Methods.Sensors (Basel, Switzerland) · 2020Review
- Radiation-Activated Pre-Differentiated Retinal Tissue Monitored by Acoustic Wave Biosensor.Sensors (Basel, Switzerland) · 2020Article
- Development of SPR Imaging-Impedance Sensor for Multi-Parametric Living Cell Analysis.Sensors (Basel, Switzerland) · 2019Article
- Design and Development of Microscale Thickness Shear Mode (TSM) Resonators for Sensing Neuronal Adhesion.Frontiers in neuroscience · 2019Article
- On the Measurement of Energy Dissipation of Adhered Cells with the Quartz Microbalance with Dissipation Monitoring.Analytical chemistry · 2018Article
- Quartz Crystal Microbalance With Dissipation Monitoring: A Powerful Method to Predict theFrontiers in bioengineering and biotechnology · 2018Review
- Ultra-rapid, sensitive and specific digital diagnosis of HIV with a dual-channel SAW biosensor in a pilot clinical study.NPJ digital medicine · 2018Article
- Impedance-Based Living Cell Analysis for Clinical Diagnosis of Type I Allergy.Sensors (Basel, Switzerland) · 2017Article
- On-Line Monitoring the Growth of E. coli or HeLa Cells Using an Annular Microelectrode Piezoelectric Biosensor.International journal of environmental research and public health · 2016Article
- Real-time measurement of Plasmodium falciparum-infected erythrocyte cytoadhesion with a quartz crystal microbalance.Malaria journal · 2016Article
- Non-Invasive Acoustical sensing of Drug-Induced Effects on the Contractile Machinery of Human Cardiomyocyte Clusters.PloS one · 2015Article
- Chemically grafted fibronectin for use in QCM-D cell studies.Biosensors & bioelectronics · 2014Article
- Real-time monitoring of cell mechanical changes induced by endothelial cell activation and their subsequent binding with leukemic cell lines.Biosensors & bioelectronics · 2014Article
Corrections and comments
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Authors and funding
2 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Acoustic biosensors offer the possibility to analyse cell attachment and spreading. This is due to the offered speed of detection, the real-time non-invasive approach and their high sensitivity not only to mass coupling, but also to viscoelastic changes occurring close to the sensor surface. Quartz crystal microbalance (QCM) and surface acoustic wave (Love-wave) systems have been used to monitor the adhesion of animal cells to various surfaces and record the behaviour of cell layers under various conditions. The sensors detect cells mostly via their sensitivity in viscoelasticity and mechanical properties. Particularly, the QCM sensor detects cytoskeletal rearrangements caused by specific drugs affecting either actin microfilaments or microtubules. The Love-wave sensor directly measures cell/substrate bonds via acoustic damping and provides 2D kinetic and affinity parameters. Other studies have applied the QCM sensor as a diagnostic tool for leukaemia and, potentially, for chemotherapeutic agents. Acoustic sensors have also been used in the evaluation of the cytocompatibility of artificial surfaces and, in general, they have the potential to become powerful tools for even more diverse cellular analysis.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.