ReviewEMBO reports2011
The emerging functions of septins in metazoans.
Review in EMBO reports, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 72 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
72 citing papers in PubMed, 127 citations in OpenAlex.
- Septin crosstalk with microtubules and actin is regulated by a GSK3-dependent phosphoswitch.bioRxiv : the preprint server for biology · 2026Article
- Mammalian innate antiviral defenses: beyond interferon.Journal of virology · 2025Review
- Septins in the nervous system: from cytoskeletal dynamics to neurological disorders.Cell communication and signaling : CCS · 2025Review
- Unearthing the role of septins in viral infections.Bioscience reports · 2024Review
- Septins regulate border cell surface geometry, shape, and motility downstream of Rho in Drosophila.Developmental cell · 2023Article
- Whi3 mnemon association with endoplasmic reticulum membranes confines the memory of deceptive courtship to the yeast mother cell.Current biology : CB · 2022Article
- Drosophila septin interacting protein 1 regulates neurogenesis in the early developing larval brain.Scientific reports · 2022Article
- Insights of roles played by septins in pathogenic fungi.Virulence · 2021Review
- Dynamic Structure of Yeast Septin by Fast Fluctuation-Enhanced Structured Illumination Microscopy.Microorganisms · 2021Article
- Septins in Infections: Focus on Viruses.Pathogens (Basel, Switzerland) · 2021Review
- Production and analysis of a mammalian septin hetero-octamer complex.Cytoskeleton (Hoboken, N.J.) · 2020Article
- The dynamic nuclear periphery as a facilitator of gamete health and rejuvenation.Current genetics · 2020Review
- SEPT7 Interacts with KIF20A and Regulates the Proliferative State of Neural Progenitor Cells During Cortical Development.Cerebral cortex (New York, N.Y. : 1991) · 2020Article
- Guanidine hydrochloride reactivates an ancient septin hetero-oligomer assembly pathway in budding yeast.eLife · 2020Article
- Distinct segregation patterns of yeast cell-peripheral proteins uncovered by a method for protein segregatome analysis.Proceedings of the National Academy of Sciences of the United States of America · 2019Article
- Septin-2 is overexpressed in epithelial ovarian cancer and mediates proliferation via regulation of cellular metabolic proteins.Oncotarget · 2019Article
- A requirement for septins and the autophagy receptor p62 in the proliferation of intracellular Shigella.Cytoskeleton (Hoboken, N.J.) · 2019Article
- Septins Recognize and Entrap Dividing Bacterial Cells for Delivery to Lysosomes.Cell host & microbe · 2018Article
- Septins suppress the release of vaccinia virus from infected cells.The Journal of cell biology · 2018Article
- Use of zebrafish to studyDisease models & mechanisms · 2018Review
12 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Septins form a subfamily of highly related GTP-binding proteins conserved from eukaryotic protists to mammals. In most cases, septins function in close association with cell membranes and the actin and microtubule cytoskeleton to regulate a wide variety of key cellular processes. Further underscoring their importance, septin abnormalities are associated with several human diseases. Remarkably, septins have the ability to polymerize into assemblies of different sizes in vitro and in vivo. In cells, these structures act in the formation of diffusion barriers and scaffolds that maintain subcellular polarity. Here, we focus on the emerging roles of vertebrate septins in ciliogenesis, neurogenesis, tumorigenesis and host-pathogen interactions, and discuss whether unifying themes underlie the molecular function of septins in health and disease.
Indexed as
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.