Evidence map›Paper›PMID 21994902›Full record

ArticleAmerican journal of cancer research2011

mRNA and microRNA expression patterns in adrenocortical cancer.

Adrienn Zsippai, Diana Rita Szabó, Peter M Szabó, Zsófia Tömböl, Melinda R Bendes, Zoltán Nagy, Károly Rácz, Peter Igaz

Open access · greenAbstract read
In one paragraph

Article in American journal of cancer research, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
1.0field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 19 citations in OpenAlex.

  1. Pediatric adrenocortical carcinoma.Frontiers in endocrinology · 2022
    Review
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  10. Molecular markers of adrenocortical tumors.Journal of surgical oncology · 2012
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Adrienn Zsippai2 Department of Medicine, Faculty of Medicine, Semmelweis University Szentkirályi str. 46. H-1088 Budapest, Hungary.
Diana Rita Szabó
Peter M Szabó
Zsófia Tömböl
Melinda R Bendes
Zoltán Nagy
Károly Rácz
Peter Igaz
Semmelweis University · HU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Adrenocortical cancer is a rare tumor and its prognosis is poor. Although numerous tumor-associated genetic and signal transduction alterations have been described to date, its pathogenesis is still unclear. Hybridization-based DNA microarray approaches may reveal significant gene expression alterations and may thus contribute to a better understanding of tumorigenesis and may identify molecular markers applicable for the distinction of benign and malignant lesions. Beside gene expression patterns, studies on microRNAs seem to be useful, as well. Novel therapeutical targets might be established by these approaches. In this review, the authors attempt to summarize the main findings of mRNA and microRNA expression microarray studies performed to date in adrenocortical cancer including a recent meta-analysis of gene expression data and present novel pathogenic pathways.

Indexed as

Adrenocortical tumorgene expressionmeta-analysismicroarraymicroRNA

Identifiers

PMID21994902
PMCPMC3189823
OpenAlexW51030972

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.