ArticleInternational journal of hepatology2012
IgG4 Cholangiopathy.
Article in International journal of hepatology, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
What it found
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
10 citing papers in PubMed.
- Immunoglobulin G4 Cholangiopathy Masquerading as a Klatskin Tumor: An Interesting Case.Cureus · 2021Article
- Obstructive Jaundice Is Not Always Surgical!ACG case reports journal · 2019Article
- IgG4-related sclerosing cholangitis: all we need to know.Journal of gastroenterology · 2016Review
- IgG4-Associated Cholangitis Can Mimic Hilar Cholangiocarcinoma.Gut and liver · 2015Article
- Autoimmune pancreatitis mimicking Klatskin tumour on radiology.BMJ case reports · 2015Article
- IgG4-Seronegative Autoimmune Pancreatitis and Sclerosing Cholangitis.Case reports in gastrointestinal medicine · 2015Article
- Immunoglobulin G4-related pancreatic and biliary diseases.Canadian journal of gastroenterology = Journal canadien de gastroenterologie · 2013Review
- Diagnostic Dilemma in a Patient with Jaundice: How to Differentiate between Autoimmune Pancreatitis, Primary Sclerosing Cholangitis and Pancreas Carcinoma.Case reports in gastroenterology · 2012Article
- Klatskin-like lesions.HPB surgery : a world journal of hepatic, pancreatic and biliary surgery · 2012Article
- Non-neoplastic cholangiopathies: an algorithmic approach.Radiologia brasileiraReview
Corrections and comments
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Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
IgG4 cholangiopathy can involve any level of the biliary tree which exhibits sclerosing cholangitis or pseudotumorous hilar lesions. Most cases are associated with autoimmune pancreatitis, an important diagnostic clue. Without autoimmune pancreatitis, however, the diagnosis of IgG4-cholangiopathy is challenging. Indeed such cases have been treated surgically. IgG4-cholangiopathy should be diagnosed based on serological examinations including serum IgG4 concentrations, radiological features, and histological evidence of IgG4(+) plasma cell infiltration. Steroid therapy is very effective even at disease relapse. A Th2-dominant immune response or the activation of regulatory T cells seems to be involved in the underlying immune reaction. It is still unknown why IgG4 levels are specifically elevated in patients with this disease. IgG4 might be secondarily overexpressed by Th2 or regulatory cytokines given the lack of evidence that IgG4 is an autoantibody.
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.