ReviewViruses2011
Picornavirus subversion of the autophagy pathway.
Review in Viruses, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
21 citing papers in PubMed.
- The Dual Roles of Autophagy in Important Picornaviruses Infecting Livestock and Poultry.Veterinary sciences · 2026Review
- Type II grass carp reovirus utilizes autophagosomes for viroplasm formation and subclinical persistent infection.Journal of virology · 2025Article
- Dengue virus exploits autophagy vesicles and secretory pathways to promote transmission by human dendritic cells.Frontiers in immunology · 2024Article
- HSBP1 Is a Novel Interactor of FIP200 and ATG13 That Promotes Autophagy Initiation and Picornavirus Replication.Frontiers in cellular and infection microbiology · 2021Article
- "Repair Me if You Can": Membrane Damage, Response, and Control from the Viral Perspective.Cells · 2020Review
- Regulation of Apoptosis by Enteroviruses.Frontiers in microbiology · 2020Review
- A second open reading frame in human enterovirus determines viral replication in intestinal epithelial cells.Nature communications · 2019Article
- Autophagy Related-Protein 16-1 Up-Regulated in Hepatitis B Virus-Related Hepatocellular Carcinoma and Impaired Apoptosis.Gastroenterology research · 2018Article
- Phospholipid synthesis fueled by lipid droplets drives the structural development of poliovirus replication organelles.PLoS pathogens · 2018Article
- Comprehending a Killer: The Akt/mTOR Signaling Pathways Are Temporally High-Jacked by the Highly Pathogenic 1918 Influenza Virus.EBioMedicine · 2018Article
- Hijacking of multiple phospholipid biosynthetic pathways and induction of membrane biogenesis by a picornaviral 3CD protein.PLoS pathogens · 2018Article
- Extracellular Vesicles in Herpes Viral Spread and Immune Evasion.Frontiers in microbiology · 2018Article
- Turnip Mosaic Virus Counteracts Selective Autophagy of the Viral Silencing Suppressor HCpro.Plant physiology · 2018Article
- Coxsackievirus B Escapes the Infected Cell in Ejected Mitophagosomes.Journal of virology · 2017Article
- Human genome-wide RNAi screen reveals host factors required for enterovirus 71 replication.Nature communications · 2016Article
- Enterovirus 71-induced autophagy increases viral replication and pathogenesis in a suckling mouse model.Journal of biomedical science · 2014Article
- A LC3-interacting motif in the influenza A virus M2 protein is required to subvert autophagy and maintain virion stability.Cell host & microbe · 2014Article
- Interplay of autophagy and apoptosis during murine cytomegalovirus infection of RPE cells.Molecular vision · 2014Article
- Echovirus 7 entry into polarized caco-2 intestinal epithelial cells involves core components of the autophagy machinery.Journal of virology · 2014Article
- Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
While autophagy has been shown to act as an anti-viral defense, the Picornaviridae avoid and, in many cases, subvert this pathway to promote their own replication. Evidence indicates that some picornaviruses hijack autophagy in order to induce autophagosome-like membrane structures for genomic RNA replication. Expression of picornavirus proteins can specifically induce the machinery of autophagy, although the mechanisms by which the viruses employ autophagy appear to differ. Many picornaviruses up-regulate autophagy in order to promote viral replication while some members of the family also inhibit degradation by autolysosomes. Here we explore the unusual relationship of this medically important family of viruses with a degradative mechanism of innate immunity.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.