Evidence map›Paper›PMID 21994790›Full record

ReviewViruses2011

Cell surface markers in HTLV-1 pathogenesis.

Andrea K Kress, Ralph Grassmann, Bernhard Fleckenstein

Open access · goldAbstract readReview
In one paragraph

Review in Viruses, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
0.5field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 27 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
  4. Article
  5. Article
  6. Review
  7. Article
  8. Review
  9. Article
  10. Article
  11. Review
  12. Article
  13. Six Cases of CD20-Positive Adult T-Cell Leukemia.Journal of clinical and experimental hematopathology : JCEH · 2016
    Article
  14. Article
  15. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Andrea K KressInstitute of Clinical and Molecular Virology, Friedrich-Alexander-Universität Erlangen-Nürnberg, Erlangen, Germany. Andrea.Kress@viro.med.uni-erlangen.de
Ralph Grassmann
Bernhard Fleckenstein
Friedrich-Alexander-Universität Erlangen-Nürnberg · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The phenotype of HTLV-1-transformed CD4(+) T lymphocytes largely depends on defined viral effector molecules such as the viral oncoprotein Tax. In this review, we exemplify the expression pattern of characteristic lineage markers, costimulatory receptors and ligands of the tumor necrosis factor superfamily, cytokine receptors, and adhesion molecules on HTLV-1-transformed cells. These molecules may provide survival signals for the transformed cells. Expression of characteristic surface markers might therefore contribute to persistence of HTLV-1-transformed lymphocytes and to the development of HTLV-1-associated disease.

Indexed as

BiomarkersCD4-Positive T-LymphocytesCell Adhesion MoleculesCell DifferentiationCell Line, TransformedCell ProliferationCell Transformation, ViralCostimulatory and Inhibitory T-Cell ReceptorsGene Products, taxHumansHuman T-lymphotropic virus 1Leukemia-Lymphoma, Adult T-CellParaparesis, Tropical SpasticPhenotypeReceptors, CytokineSignal TransductionBiomarkersCell Adhesion MoleculesCostimulatory and Inhibitory T-Cell ReceptorsGene Products, taxReceptors, Cytokinetax protein, Human T-lymphotrophic virus 1ATLLcytokine receptordifferentiationHAM/TSPHTLV-1interleukinoncoproteinphenotypeTaxTNFR

Identifiers

PMID21994790
PMCPMC3185802
OpenAlexW2156375506

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.