Evidence map›Paper›PMID 21994712›Full record

ArticleViruses2010

JaPaFi: A Novel Program for the Identification of Highly Conserved DNA Sequences.

Aliya Sadeque, Marina Barsky, Francesco Marass, Peter Kruczkiewicz, Chris Upton

Abstract read
In one paragraph

Article in Viruses, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Aliya SadequeDepartment of Biochemistry and Microbiology, University of Victoria, Victoria, BC, V8W 3P6, Canada.
Marina BarskyDepartment of Computer Science, University of Victoria, Victoria, BC, V8W 3P6, Canada.
Francesco MarassDepartment of Biochemistry and Microbiology, University of Victoria, Victoria, BC, V8W 3P6, Canada.
Peter KruczkiewiczDepartment of Biochemistry and Microbiology, University of Victoria, Victoria, BC, V8W 3P6, Canada.
Chris UptonDepartment of Biochemistry and Microbiology, University of Victoria, Victoria, BC, V8W 3P6, Canada.ORCID 0000-0002-9019-8967

Funding

NIAID NIH HHS HHSN266200400036C
6 · The paper itself

Abstract

We describe the use of Java Pattern Finder (JaPaFi) to identify short (<100 nt) highly conserved sequences in a series of poxvirus genomes. The algorithm utilizes pattern matching to identify approximate matches appearing at least once in each member of a set of genomes; a key feature is that the genomes do not need to be aligned. The user simply specifies the genomes to search, minimum length of sequences to find and the maximum number of mismatches and indels allowed. Many of the most highly conserved segments contain poxvirus promoter elements.

Indexed as

approximate matchbioinformaticsconserved functionhighly conserved sequencesJaPaFiPoxvirus

Identifiers

PMID21994712
PMCPMC3185747

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.