Evidence map›Paper›PMID 21994635›Full record

ArticleViruses2010

The complexity of antibody-dependent enhancement of dengue virus infection.

Maria G Guzman, Susana Vazquez

Abstract read
In one paragraph

Article in Viruses, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 94 papers.

0numbers the graph read from it
0cells of the map it votes in
94citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

94 citing papers in PubMed.

  1. Trial
  2. Article
  3. Article
  4. Article
  5. Dengue Vaccines.Current topics in microbiology and immunology · 2026
    Review
  6. Article
  7. Article
  8. Pharmaceuticals (Basel, Switzerland) · 2025
    Article
  9. Review
  10. Review
  11. Review
  12. Review
  13. Article
  14. Seroprevalence of Zika virus and dengue virus infections in migrants in Italy.Frontiers in cellular and infection microbiology · 2025
    Article
  15. Review
  16. Article
  17. Review
  18. Article
  19. Review
  20. Article

34 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Maria G GuzmanDepartment of Virology, PAHO/WHO Collaborating Center for the Study of Dengue and its Vector, "Pedro Kouri" Tropical Medicine Institute of Havana, Cuba; E-Mail: ciipk@ipk.sld.cu.
Susana Vazquez

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Antibody-dependent enhancement (ADE) has been proposed as a mechanism to explain dengue hemorrhagic fever (DHF) in the course of a secondary dengue infection. Very recently, Dejnirattisai et al., 2010 [1], published an important article supporting the involvement of anti-prM antibodies in the ADE phenomenon. The complexity of ADE in the context of a secondary dengue infection is discussed here.

Indexed as

ADEcleavagedenguedengue hemorrhagic feverneutralizationprM

Identifiers

PMID21994635
PMCPMC3185591

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.