ArticleThe Journal of cell biology1990
A rapid posttranslational myristylation of a 68-kD protein in D. discoideum.
Article in The Journal of cell biology, 1990. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
6 citing papers in PubMed, 35 citations in OpenAlex.
- Coenzyme A dependent myristoylation and demyristoylation in the regulation of bovine spleen N-myristoyltransferase.Molecular and cellular biochemistry · 1996Article
- Mechanisms of action of NIP71 on N-myristoyltransferase activity.Molecular and cellular biochemistry · 1994Article
- Pheromone action regulates G-protein alpha-subunit myristoylation in the yeast Saccharomyces cerevisiae.Proceedings of the National Academy of Sciences of the United States of America · 1993Article
- Two distinct populations of ARF bound to Golgi membranes.The Journal of cell biology · 1993Article
- Identification, purification and characterization of a membrane-associated N-myristoyltransferase inhibitor protein from bovine brain.The Biochemical journal · 1993Article
- Mammalian myristoyl CoA: protein N-myristoyltransferase.Molecular and cellular biochemistryArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 1 country.
Funding
Abstract
Cells incubated with [3H]myristate were shown to rapidly and specifically acylate a 68-kD protein, p68, in a developmentally-regulated manner. The fatty acid incorporated into p68 was identified as myristate, and is linked to the protein via an amide bond, apparently to an NH2-terminal glycine. The acylation of p68 in D. discoideum displays some unusual properties. Unexpectedly, myristylation of p68 is a posttranslational event and occurs in the presence of inhibitors of protein synthesis. Another unusual finding was that although p68 is a stable protein, the acyl moiety is removed with a half time of approximately 15 min.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.