Evidence map›Paper›PMID 21993999›Full record

Trial reportJournal of general internal medicine2012

Electronic risk alerts to improve primary care management of chest pain: a randomized, controlled trial.

Thomas D Sequist, Shane M Morong, Amy Marston, Carol A Keohane, E Francis Cook, E John Orav, Thomas H Lee

Open access · bronzeAbstract readRandomized Controlled Trial
In one paragraph

Trial report in Journal of general internal medicine, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 3 pooled it
0.8field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 3 syntheses or guidelines pooled it, 15 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Trial
  5. Article
  6. Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Thomas D SequistDivision of General Medicine and Primary Care, Brigham and Women's Hospital, 1620 Tremont Street, Boston, MA 02120, USA. tsequist@partners.org
Shane M Morong
Amy Marston
Carol A Keohane
E Francis Cook
E John Orav
Thomas H Lee
Brigham and Women's Hospital · USHarvard Vanguard Medical Associates · US

Funding

Sequist:Can Risk Score Alerts Improve Office Care for Chest Pain?R18HS017075 · AHRQ · BRIGHAM AND WOMEN'S HOSPITAL · PI SEQUIST, THOMAS D · 2007 to 2009
$681k
AHRQ HHS R18 HS017075AHRQ HHS R18HS017075
6 · The paper itself

Abstract

backgroundThe primary care evaluation of chest pain represents a significant diagnostic challenge.

objectiveTo determine if electronic alerts to physicians can improve the quality and safety of chest pain evaluations. DESIGN AND

participantsRandomized, controlled trial conducted between November 2008 and January 2010 among 292 primary care clinicians caring for 7,083 adult patients with chest pain and no history of cardiovascular disease.

interventionClinicians received alerts within the electronic health record during office visits for chest pain. One alert recommended performance of an electrocardiogram and administration of aspirin for high risk patients (Framingham Risk Score (FRS) ≥ 10%), and a second alert recommended against performance of cardiac stress testing for low risk patients (FRS < 10%). MAIN MEASURES: The primary outcomes included performance of an electrocardiogram and administration of aspirin therapy for high risk patients; and avoidance of cardiac stress testing for low risk patients. KEY

resultsThe majority (81%) of patients with chest pain were classified as low risk. High risk patients were more likely than low risk patients to be evaluated in the emergency department (11% versus 5%, p < 0.01) and to be hospitalized (7% versus 3%, p < 0.01). Acute myocardial infarction occurred among 26 (0.4%) patients, more commonly among high risk compared to low risk patients (1.1% versus 0.2%, p < 0.01). Among high risk patients, there was no difference between the intervention and control groups in rates of performing electrocardiograms (51% versus 48%, p = 0.33) or administering aspirin (20% versus 18%, p = 0.43). Among low risk patients, there was no difference between intervention and control groups in rates of cardiac stress testing (10% versus 9%, p = 0.40).

conclusionsPrimary care management of chest pain is suboptimal for both high and low risk patients. Electronic alerts do not increase risk-appropriate care for these patients.

Indexed as

Clinical AlarmsChest PainConfidence IntervalsFemaleHealth Care SurveysHumansLogistic ModelsMaleMiddle AgedMyocardial InfarctionQuality of Health CareRisk AssessmentStatistics as TopicUnited States

Identifiers

PMID21993999
PMCPMC3304044
OpenAlexW2020594593

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.