ArticleThe international journal of cardiovascular imaging2011
The effect of calcium score on the diagnostic accuracy of coronary computed tomography angiography.
Article in The international journal of cardiovascular imaging, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers, 1 of them a synthesis that pooled it.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
23 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Computed tomography angiography versus Agatston score for diagnosis of coronary artery disease in patients with stable chest pain: individual patient data meta-analysis of the international COME-CCT Consortium.European radiology · 2022Pooled it
- The Diagnostic Performance of Coronary CT Angiography for the Assessment of Coronary Stenosis in Calcified Plaque.PloS one · 2016Trial
- Diagnostic Performance of a Novel AI-Guided Coronary Computed Tomography Algorithm for Predicting Myocardial Ischemia (AI-QCTJournal of the Society for Cardiovascular Angiography & Interventions · 2026Article
- Calcific versus non-calcific plaque: a CAD-RADS and FFRCT study.The international journal of cardiovascular imaging · 2025Article
- The effectiveness of coronary computed tomography angiography and functional testing for the diagnosis of obstructive coronary artery disease: results from the individual patient data Collaborative Meta-Analysis of Cardiac CT (COME-CCT).Insights into imaging · 2024Article
- Cardiovascular Computed Tomography in the Diagnosis of Cardiovascular Disease: Beyond Lumen Assessment.Journal of cardiovascular development and disease · 2024Review
- Diagnostic performance of 3D cardiac magnetic resonance perfusion in elderly patients for the detection of coronary artery disease as compared to fractional flow reserve.European radiology · 2023Article
- Hybrid model of CT-fractional flow reserve, pericoronary fat attenuation index and radiomics for predicting the progression of WMH: a dual-center pilot study.Frontiers in cardiovascular medicine · 2023Article
- Added Value of Computed Tomography Virtual Intravascular Endoscopy in the Evaluation of Coronary Arteries with Stents or Plaques.Diagnostics (Basel, Switzerland) · 2022Article
- Current and Future Applications of Artificial Intelligence in Coronary Artery Disease.Healthcare (Basel, Switzerland) · 2022Review
- 3D-Printed Coronary Plaques to Simulate High Calcification in the Coronary Arteries for Investigation of Blooming Artifacts.Biomolecules · 2021Article
- The effect of coronary calcification on diagnostic performance of machine learning-based CT-FFR: a Chinese multicenter study.European radiology · 2021Article
- Debates over NICE Guideline Update: What Are the Roles of Nuclear Cardiology in the Initial Evaluation of Stable Chest Pain?Nuclear medicine and molecular imaging · 2019Review
- Synchrotron radiation computed tomography assessment of calcified plaques and coronary stenosis with different slice thicknesses and beam energies on 3D printed coronary models.Quantitative imaging in medicine and surgery · 2019Article
- Cardiovascular Imaging Techniques in Systemic Rheumatic Diseases.Frontiers in medicine · 2018Review
- An investigation of correlation between left coronary bifurcation angle and hemodynamic changes in coronary stenosis by coronary computed tomography angiography-derived computational fluid dynamics.Quantitative imaging in medicine and surgery · 2017Article
- Comparison of the Left Main Coronary Bifurcating Angle among Patients with Normal, Non-significantly and Significantly Stenosed Left Coronary Arteries.Scientific reports · 2017Article
- Prognostic Value of Coronary Artery Calcium Score for Determination of Presence and Severity of Coronary Artery Disease.Polish journal of radiology · 2017Article
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8 authors.
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Abstract
The influence of coronary calcification on the diagnostic performance of coronary computed tomography angiography (CTA) remains controversial. This study attempts to assess the effect of coronary calcium score (CS) on the diagnostic accuracy of detecting coronary artery disease (CAD) using 64-row multidetector computed tomography (MDCT). Over a period of 2 years and 9 months, 113 symptomatic patients (37-87 year-old, mean 62.3, 92 males) underwent 64-row MDCT for coronary CS and CTA. All had conventional coronary angiography (CCA) within 90 (mean 9.6) days. Coronary CTA was evaluated with CCA as the gold standard. Of 113 patients, 18 patients had a CS of 0, 18 had scores between 1 and 100, 27 between 101 and 400, and 50 had scores >400. With respect to patient-based analysis, the accuracy of CTA was 90.3%, the sensitivity was 95%, and the specificity was 78.8%. Regarding patients with CS > 400, the accuracy, sensitivity, and specificity were 92, 95.6, and 60%, respectively. On vessel-based analysis, the specificity of CTA in different vessels with CS < [double bond] 400 and CS > 400 was as follows: right coronary artery 87.1% versus 87.5% (P = 0.924); left main artery 94.8% versus 66.7% (P = 0.173); left anterior descending artery 77.1% versus 27.3% (P = 0.001); and left circumflex artery 83.3% versus 42.8% (P = 0.011). A high CS does not significantly affect the diagnostic accuracy and sensitivity of CTA; however, it significantly decreases the specificity, particularly the left anterior descending and left circumflex arteries.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.