Evidence map›Paper›PMID 21993761›Full record

ArticleNature2011

InsP3R channel gating altered by clustering?

Horia Vais, J Kevin Foskett, Don-On Daniel Mak

Abstract readComment
In one paragraph

Article in Nature, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Spatial-temporal patterning of CaSeminars in cell & developmental biology · 2019
    Review
  2. Review
  3. Article
  4. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

3 authors.

Horia VaisDepartment of Physiology, University of Pennsylvania Perleman School of Medicine, Philadelphia, Pennsylvania 19104, USA.
J Kevin Foskett
Don-On Daniel Mak

Funding

Multi-scale observation and modeling of IP3/Ca signalingR01GM065830 · NIGMS · UNIVERSITY OF CALIF-LOS ALAMOS NAT LAB · PI MAK, DON-ON DANIEL, PARKER, IAN · 2002 to 2017
$10.7M
MOLECULAR PHYSIOLOGY OF MAMMALIAN INSP3 RECEPTORSR01MH059937 · NIMH · UNIVERSITY OF PENNSYLVANIA · PI FOSKETT, JAMES KEVIN · 2000 to 2014
$5.0M
Rapid kinetics of single InsP3R channel regulationR01GM074999 · NIGMS · UNIVERSITY OF PENNSYLVANIA · PI MAK, DON-ON DANIEL · 2005 to 2010
$1.4M
NIGMS NIH HHS R01 GM065830NIGMS NIH HHS R01 GM074999NIMH NIH HHS R01 MH059937
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Calcium SignalingAnimalsCalciumInositol 1,4,5-TrisphosphateInositol 1,4,5-Trisphosphate ReceptorsCalciumInositol 1,4,5-TrisphosphateInositol 1,4,5-Trisphosphate Receptors

Identifiers

PMID21993761
PMCPMC3273963

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.