ArticleEuropean archives of psychiatry and clinical neuroscience2012
Depression is associated with low levels of 25-hydroxyvitamin D among Jordanian adults: results from a national population survey.
Article in European archives of psychiatry and clinical neuroscience, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 4 of them syntheses that pooled it.
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Who cites it
21 citing papers in PubMed, 4 syntheses or guidelines pooled it, 46 citations in OpenAlex.
- Vitamin D and depression in adults: A systematic review.Biomolecules & biomedicine · 2025Pooled it
- Gender differences in depression in representative national samples: Meta-analyses of diagnoses and symptoms.Psychological bulletin · 2017Pooled it
- Non-skeletal health effects of vitamin D supplementation: A systematic review on findings from meta-analyses summarizing trial data.PloS one · 2017Pooled it
- Serum 25-hydroxyvitamin D levels and the risk of depression: a systematic review and meta-analysis.The journal of nutrition, health & aging · 2013Pooled it
- Effect of an vitamin D deficiency on depressive symptoms in child and adolescent psychiatric patients - a randomized controlled trial: study protocol.BMC psychiatry · 2018Trial
- The Role of Vitamin D in the Management of Major Depressive Disorder: A Systematic Review.Pharmaceuticals (Basel, Switzerland) · 2025Review
- Serum Vitamin D and Depressive Symptomatology among Boston-Area Puerto Ricans.The Journal of nutrition · 2020Article
- Vitamin D Doses from Solar Ultraviolet and Dietary Intakes in Patients with Depression: Results of a Case-Control Study.Nutrients · 2020Article
- Vitamin D in the Middle East and North Africa.Bone reports · 2018Article
- Vitamin D and mental health in children and adolescents.European child & adolescent psychiatry · 2017Review
- [Nutrition and mental diseases : Focus depressive disorders].Der Nervenarzt · 2017Review
- Association of circulating 25-hydroxyvitamin D with mental well-being in a population-based, nationally representative sample of German adolescents.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2016Article
- Vitamin D deficiency in Swiss elite wheelchair athletes.Spinal cord · 2016Article
- Associations between vitamin D levels and depressive symptoms in healthy young adult women.Psychiatry research · 2015Article
- Serum 25-Hydroxyvitamin D in Patients with Major Depressive Disorder.Iranian journal of public health · 2015Article
- Glia in the cytokine-mediated onset of depression: fine tuning the immune response.Frontiers in cellular neuroscience · 2015Review
- Antidepressants differentially related to 1,25-(OH)₂ vitamin D₃ and 25-(OH) vitamin D₃ in late-life depression.Translational psychiatry · 2014Article
- Low vitamin D status and suicide: a case-control study of active duty military service members.PloS one · 2013Article
- Do current screening recommendations allow for early detection of lithium-induced hyperparathyroidism in patients with bipolar disorder?International journal of bipolar disorders · 2013Article
- From pathophysiological aspects towards unravelling the neurobiological background of cognitive deficits.European archives of psychiatry and clinical neuroscience · 2012Article
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Authors and funding
6 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Although low serum 25-hydroxyvitamin D (25(OH)D) and elevated serum parathyroid hormone (PTH) have been associated with depression in clinical settings, this link in community-dwelling individuals is inconclusive. The present study aimed at examining the association between serum 25(OH)D and PTH levels and the presence of depression in a national population-based household sample of 4,002 Jordanian participants aged ≥25 years. The DASS21 depression scale was used to screen for depression, and serum concentrations of 25(OH)D and PTH were measured by radioimmunoassay. Multiple logistic regression models were used to explore the association between serum 25(OH)D and PTH levels and depression. The unadjusted odds ratio (OR) decreased linearly with increasing quartiles of serum 25(OH)D (P(trend) = 0.00). The OR for having depression was significantly higher among individuals in the first and second quartiles (OR = 1.4, 1.23, respectively) than among those in the fourth quartile (P values = 0.00 and 0.03, respectively). This relationship remained significant after adjusting for age, sex, marital status, education, BMI, serum creatinine, number of chronic diseases (OR = 1.39 and 1.21 and P values = 0.00 and 0.05, respectively) and after further adjustment for exercise, altitude, and smoking (OR = 1.48 and 1.24, respectively, and P values = 0.00 and 0.03, respectively). No significant association was found between serum PTH levels and depression. The decrease in risk of depression among participants started to be significant with serum 25(OH) D levels higher than 42.3 ng/ml (lower limit of the range of the third quartile). This value may help pinpoint the desirable level of serum 25(OH)D to be attained to help aid the prevention and treatment of depression.
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