Evidence map›Paper›PMID 21993222›Full record

ReviewMolecules (Basel, Switzerland)2011

A survey of marine natural compounds and their derivatives with anti-cancer activity reported in 2010.

Marc Schumacher, Mareike Kelkel, Mario Dicato, Marc Diederich

Abstract readReview
In one paragraph

Review in Molecules (Basel, Switzerland), 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Review
  6. Article
  7. Review
  8. Review
  9. Article
  10. Article
  11. Review
  12. Article
  13. Marine invertebrate natural products for anti-inflammatory and chronic diseases.Evidence-based complementary and alternative medicine : eCAM · 2013
    Review
  14. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Marc SchumacherLaboratoire de Biologie Moléculaire et Cellulaire du Cancer, Fondation de Recherche Cancer et Sang, Hôpital Kirchberg, 9, rue Steichen L-2540, Luxembourg. marc.diederich@lbmcc.lu
Mareike Kelkel
Mario Dicato
Marc Diederich

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Although considerable progress in oncology therapeutics has been achieved in the last century, cancer remains one of major death causes in the World and for this reason, the development of novel cancer drugs remains a pressing need. Natural marine compounds represent an interesting source of novel leads with potent chemotherapeutic or chemo-preventive activities. In the last decades, structure-activity-relationship studies have led to the development of naturally-derived or semi-synthetic analogues with improved bioactivity, a simplified synthetic target or less toxicity. We aim here to review a selection of natural compounds with reported anticancer activity isolated of marine sources and their associated analogues published in 2010.

Indexed as

Antineoplastic AgentsBiological ProductsAnimalsAquatic OrganismsDrug Screening Assays, AntitumorHumansMolecular StructureNeoplasmsPlant PreparationsStructure-Activity RelationshipAntineoplastic AgentsBiological ProductsPlant Preparations

Identifiers

PMID21993222
PMCPMC6264395

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.