ArticleWorld journal of surgical oncology2011
Partial nephrectomy using porcine small intestinal submucosa.
Article in World journal of surgical oncology, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
6 citing papers in PubMed, 12 citations in OpenAlex.
- The application of small intestinal submucosa in tissue regeneration.Materials today. Bio · 2024Review
- Positive surgical margins in nephron-sparing surgery: risk factors and therapeutic consequences.World journal of surgical oncology · 2014Review
- Survival advantage of partial over radical nephrectomy in patients presenting with localized renal cell carcinoma.BMC cancer · 2014Article
- Traumatic rectourethral fistula repair: A potential application of porcine small intestinal submucosa.Indian journal of urology : IJU : journal of the Urological Society of India · 2013Article
- [The use of Surgisis® optimizes and simplifies partial nephrectomy for large renal tumors].Der Urologe. Ausg. A · 2013Article
- Renal Cell Carcinoma Update: News from the AUA, EAU, and ASCO Annual Meetings 2011.ISRN urology · 2012Article
Corrections and comments
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Authors and funding
8 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundWhenever technically feasible and oncologically justified, nephron-sparing surgery is the current standard of care for localized renal cell carcinomas (RCC). The main complications of partial nephrectomy, especially for large and centrally located tumors, are urinary leakage and parenchymal bleeding. We prospectively evaluated the pros and cons of using porcine small intestinal submucosa (SIS, Surgisis®) to close the renal defect after nephron-sparing surgery.
methodsWe used Surgisis® (Cook medical, Bloomington, IN, USA) to secure and compress the capsular defect after tumor resection in 123 patients submitted to 129 partial nephrectomies between August 2003 and February 2011.
resultsThe median tumor size was 3.7 cm (range 1.1-13.0 cm). Procedures were performed with cold ischemia in 24 cases (18.2%), with warm ischemia in 46 (35.6%), and without ischemia in 59 cases (44.8%). In the total group of patients, 4 (3.1%) developed urinary fistula, and only 2 (1.6%) required postoperative transfusions due to hemorrhage after the application of the small intestinal submucosa membrane.
conclusionSmall intestinal submucosa is an easy-to-use biomaterial for preventing complications such as postoperative bleeding and urinary fistula in nephron-sparing surgery, especially in cases where tumor excision causes significant renal capsular and/or renal pelvic defects.
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Registered trials
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