ArticleMolecular microbiology2011
The N-acetyl-D-glucosamine repressor NagC of Vibrio fischeri facilitates colonization of Euprymna scolopes.
Article in Molecular microbiology, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 36 papers.
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Who cites it
36 citing papers in PubMed, 47 citations in OpenAlex.
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- Genome-wide phenotypic profiling of transcription factors and identification of novel targets to control the virulence of Vibrio vulnificus.Nucleic acids research · 2025Article
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- A prototrophic suppressor of aJournal of bacteriology · 2024Article
- Host-derived organic acids enable gut colonization of the honey bee symbiont Snodgrassella alvi.Nature microbiology · 2024Article
- Flagella are required to coordinately activate competition and host colonization factors in response to a mechanical signal.bioRxiv : the preprint server for biology · 2024Article
- Quorum sensing inhibits interference competition among bacterial symbionts within a host.Current biology : CB · 2023Article
- Reciprocal regulation of NagC and quorum sensing systems and their roles inMicrobiology (Reading, England) · 2023Article
- Unifying themes and distinct features of carbon and nitrogen assimilation by polysaccharide-degrading bacteria: a summary of four model systems.Applied microbiology and biotechnology · 2021Review
- A lasting symbiosis: how Vibrio fischeri finds a squid partner and persists within its natural host.Nature reviews. Microbiology · 2021Review
- Vibrio fischeri imports and assimilates sulfate during symbiosis with Euprymna scolopes.Molecular microbiology · 2021Article
- The Bacterial Enhancer Binding Protein VasH Promotes Expression of a Type VI Secretion System in Vibrio fischeri during Symbiosis.Journal of bacteriology · 2020Article
- Aliivibrio wodanis as a production host: development of genetic tools for expression of cold-active enzymes.Microbial cell factories · 2019Article
- Ambient pH Alters the Protein Content of Outer Membrane Vesicles, Driving Host Development in a Beneficial Symbiosis.Journal of bacteriology · 2019Article
- Incompatibility of Vibrio fischeri Strains during Symbiosis Establishment Depends on Two Functionally RedundantJournal of bacteriology · 2019Article
- Sulfur availability for Vibrio fischeri growth during symbiosis establishment depends on biogeography within the squid light organ.Molecular microbiology · 2019Article
- The alternative sigma factor RpoQ regulates colony morphology, biofilm formation and motility in the fish pathogen Aliivibrio salmonicida.BMC microbiology · 2018Article
- Tools for Rapid Genetic Engineering of Vibrio fischeri.Applied and environmental microbiology · 2018Article
- Transcriptional characterization of Vibrio fischeri during colonization of juvenile Euprymna scolopes.Environmental microbiology · 2017Article
- Article
Corrections and comments
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Authors and funding
6 authors at 2 institutions in 2 countries.
Funding
Abstract
To successfully colonize and persist within a host niche, bacteria must properly regulate their gene expression profiles. The marine bacterium Vibrio fischeri establishes a mutualistic symbiosis within the light organ of the Hawaiian squid, Euprymna scolopes. Here, we show that the repressor NagC of V. fischeri directly regulates several chitin- and N-acetyl-D-glucosamine-utilization genes that are co-regulated during productive symbiosis. We also demonstrate that repression by NagC is relieved in the presence of N-acetyl-D-glucosamine-6-phosphate, the intracellular form of N-acetyl-D-glucosamine. We find that gene repression by NagC is critical for efficient colonization of E. scolopes. Further, our study shows that NagC regulates genes that affect the normal dynamics of host colonization.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.