Evidence map›Paper›PMID 21990339›Full record

ArticleEnvironmental health perspectives2012

Seafood contamination after the BP Gulf oil spill and risks to vulnerable populations: a critique of the FDA risk assessment.

Miriam Rotkin-Ellman, Karen K Wong, Gina M Solomon

Abstract read
In one paragraph

Article in Environmental health perspectives, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed.

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  4. Probabilistic risk assessment for high-end consumers of seafood on the northeastern Gulf coast.Journal of exposure science & environmental epidemiology · 2020
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

3 authors.

Miriam Rotkin-EllmanNatural Resources Defense Council, San Francisco, California, USA. mrotkinellman@nrdc.org
Karen K Wong
Gina M Solomon

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe BP oil spill of 2010 resulted in contamination of one of the most productive fisheries in the United States by polycyclic aromatic hydrocarbons (PAHs). PAHs, which can accumulate in seafood, are known carcinogens and developmental toxicants. In response to the oil spill, the U.S. Food and Drug Administration (FDA) developed risk criteria and established thresholds for allowable levels [levels of concern (LOCs)] of PAH contaminants in Gulf Coast seafood.

objectivesWe evaluated the degree to which the FDA's risk criteria adequately protect vulnerable Gulf Coast populations from cancer risk associated with PAHs in seafood. DISCUSSION: The FDA LOCs significantly underestimate risk from seafood contaminants among sensitive Gulf Coast populations by failing to a) account for the increased vulnerability of the developing fetus and child; b) use appropriate seafood consumption rates; c) include all relevant health end points; and d) incorporate health-protective estimates of exposure duration and acceptable risk. For benzo[a]pyrene and naphthalene, revised LOCs are between two and four orders of magnitude below the level set by the FDA. Comparison of measured levels of PAHs in Gulf seafood with the revised LOCs revealed that up to 53% of Gulf shrimp samples were above LOCs for pregnant women who are high-end seafood consumers.

conclusionsFDA risk assessment methods should be updated to better reflect current risk assessment practices and to protect vulnerable populations such as pregnant women and children.

Indexed as

Environmental ExposureFemaleFood ContaminationFood SafetyGulf of AmericaHumansMaleNeoplasmsPetroleum PollutionPolycyclic Aromatic HydrocarbonsRisk AssessmentSeafoodSex FactorsUnited StatesUnited States Food and Drug AdministrationWater Pollutants, ChemicalPolycyclic Aromatic HydrocarbonsWater Pollutants, Chemical

Identifiers

PMID21990339
PMCPMC3279436

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.