Evidence map›Paper›PMID 21989697›Full record

ReviewSeminars in respiratory and critical care medicine2011

Acute lung failure.

Rob Mac Sweeney, Daniel F McAuley, Michael A Matthay

Registry-linked trialAbstract readReview
In one paragraph

Review in Seminars in respiratory and critical care medicine, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03945409 (Validation of a New Automated System for Continuous Real-time Monitoring of Transpulmonary Pressure During Invasive Mechanical Ventilation in Patients With Acute Respiratory Failure), which is not on this map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03945409 unknown statusnot on this mapstarted 2019, after this paper: background citation

Validation of a New Automated System for Continuous Real-time Monitoring of Transpulmonary Pressure During Invasive Mechanical Ventilation in Patients With Acute Respiratory Failure

TypeobservationalSponsorUniversity of MilanRan2019 to 2022Enrolled40ConditionsAcute Respiratory Failure, Ventilator-Induced Lung InjuryArmsOPTIVENT
3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Review
  2. Article
  3. HIF and HOIL-1L-mediated PKCζ degradation stabilizes plasma membrane Na,K-ATPase to protect against hypoxia-induced lung injury.Proceedings of the National Academy of Sciences of the United States of America · 2017
    Article
  4. Lung Edema Clearance: Relevance to Patients with Lung Injury.Rambam Maimonides medical journal · 2015
    Article
  5. Review
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Rob Mac SweeneyCentre for Infection and Immunity, Queens University Belfast, Belfast, Northern Ireland.
Daniel F McAuley
Michael A Matthay

Funding

Resolution of Clinical Lung InjuryR37HL051856 · NHLBI · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI MATTHAY, MICHAEL A. · 2006 to 2015
$3.9M
RESOLUTION OF CLINICAL LUNG INJURYR01HL051856 · NHLBI · UNIVERSITY OF CALIFORNIA SAN FRANCISCO · PI MATTHAY, MICHAEL A. · 1996 to 2005
$1.7M
NHLBI NIH HHS HL51856NHLBI NIH HHS R01 HL051856NHLBI NIH HHS R37 HL051856
6 · The paper itself

Abstract

Lung failure is the most common organ failure seen in the intensive care unit. The pathogenesis of acute respiratory failure (ARF) can be classified as (1) neuromuscular in origin, (2) secondary to acute and chronic obstructive airway diseases, (3) alveolar processes such as cardiogenic and noncardiogenic pulmonary edema and pneumonia, and (4) vascular diseases such as acute or chronic pulmonary embolism. This article reviews the more common causes of ARF from each group, including the pathological mechanisms and the principles of critical care management, focusing on the supportive, specific, and adjunctive therapies for each condition.

Indexed as

Intensive Care UnitsAcute DiseaseAcute Lung InjuryCritical CareCritical IllnessHumansMultiple Organ FailureRespiratory Insufficiency

Identifiers

PMID21989697
PMCPMC3601050

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.