ReviewPlant cell reports2012
Exudation: an expanding technique for continuous production and release of secondary metabolites from plant cell suspension and hairy root cultures.
Review in Plant cell reports, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 36 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
36 citing papers in PubMed.
- Establishment and optimization of hairy root cultures of Acanthophyllum species: a novel platform for enhanced saponin production.BMC plant biology · 2026Article
- Application of Plant Growth Promoting Rhizobacteria to Improve Soil Chemical and Biological Properties and Its Effect on Growth, Physiology and Yield of Okra (Tropical life sciences research · 2025Article
- Effect of Hormonal Treatments on Cannabinoid Content Levels in Female Hemp (International journal of molecular sciences · 2025Article
- Elicitor-driven enhancement of phenolic compounds in geranium callus cultures: phytochemical profiling via LC-MS/MS and biological activities.Frontiers in chemistry · 2025Article
- Deciphering the Phytochemical Potential of Hemp Hairy Roots: A Promising Source of Cannabisins and Triterpenes as Bioactive Compounds.Molecules (Basel, Switzerland) · 2024Article
- The Metabolite Content of the Post-Culture Medium of the Tree FernInternational journal of molecular sciences · 2022Article
- Characterization of lipid droplets from a Taxus media cell suspension and their potential involvement in trafficking and secretion of paclitaxel.Plant cell reports · 2022Article
- Polyurethane Foam Rafts Supported In Vitro Cultures ofInternational journal of molecular sciences · 2021Article
- MTMS-Based Aerogel Constructs for Immobilization of Plant Hairy Roots: Effects on Proliferation ofJournal of functional biomaterials · 2021Article
- New Insight into Justicidin B Pathway and Production inInternational journal of molecular sciences · 2021Article
- Effect of methyl jasmonate and salicylic acid on the production of metabolites in cell suspensions cultures ofBiotechnology reports (Amsterdam, Netherlands) · 2020Article
- Nanosecond pulsed electrical fields enhance product recovery in plant cell fermentation.Protoplasma · 2020Article
- Salycilic Acid Induces Exudation of Crocin and Phenolics in Saffron Suspension-Cultured Cells.Plants (Basel, Switzerland) · 2020Article
- Review
- Analytical methods in strigolactone research.Plant methods · 2020Review
- Elicitation: A biotechnological tool for enhanced production of secondary metabolites in hairy root cultures.Engineering in life sciences · 2019Review
- Proteomic analysis reveals novel insights into tanshinones biosynthesis in Salvia miltiorrhiza hairy roots.Scientific reports · 2019Article
- Genomic sequencing, genome-scale metabolic network reconstruction, and in silico flux analysis of the grape endophytic fungus Alternaria sp. MG1.Microbial cell factories · 2019Article
- Comparison of elicitor-based effects on metabolic responses of Taxus × media hairy roots in perfluorodecalin-supported two-phase culture system.Plant cell reports · 2019Article
- Anti-cancer labdane diterpenoids from adventitious roots of Andrographis paniculata: augmentation of production prospect endowed with pathway gene expression.Protoplasma · 2018Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
This review addresses methods of obtaining secondary metabolites from plant cell suspension and hairy root cultures and their exudates, particularly the physiological mechanisms of secondary metabolites release and trafficking. The efficiency for product recovery of metabolites can be increased by various methods, based on the principle of continuous product release into the cultivation medium. The most common methods for metabolite recovery are elicitation, influencing membrane permeability, and in situ product removal. The biosynthetic pathways can be influenced by cultivation conditions, transformation, or application of elicitors. The membrane permeability can be altered through the application of chemical or physical treatments. Product removal can be greatly increased through a two-phase system and the introduction of absorbents into the cultivation medium. In this review, we describe some improved approaches that have proven useful in these efforts.
Indexed as
Identifiers
21987121What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.