ReviewCurrent opinion in supportive and palliative care2011
Understanding cancer-induced cachexia: imaging the flame and its fuel.
Review in Current opinion in supportive and palliative care, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
6 citing papers in PubMed, 15 citations in OpenAlex.
- Extracting value from total-body PET/CT image data - the emerging role of artificial intelligence.Cancer imaging : the official publication of the International Cancer Imaging Society · 2024Review
- Fully Automated, Semantic Segmentation of Whole-BodyJournal of nuclear medicine : official publication, Society of Nuclear Medicine · 2022Article
- Pseudo fat-saturated appearance of magnetic resonance head and neck images in 2 cachectic patients.Radiology case reports · 2020Article
- Increased skeletal intermuscular fat is associated with reduced exercise capacity in cancer survivors: a cross-sectional study.Cardio-oncology (London, England) · 2019Article
- Micro-computed tomography for non-invasive evaluation of muscle atrophy in mouse models of disease.PloS one · 2018Article
- Research on cachexia, sarcopenia and skeletal muscle in cardiology.Journal of cachexia, sarcopenia and muscle · 2012Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 3 institutions in 1 country.
Funding
Abstract
purpose of reviewOne of the most under explored and yet devastating consequences of cancer is cachexia, a condition in which the body is consumed by deranged carbohydrate, lipid and protein metabolism that is induced by inflammatory cytokines. Cachexia is associated with poor treatment outcome, fatigue and poor quality of life. Because of its multifactorial characteristics, it has been difficult to understand the impact of the tumor on body organs and the sequence of events that leads to cachexia. Such insights are critically important in identifying therapeutic strategies. RECENT
findingsThe ability to understand the interaction between the tumor and normal tissues and to noninvasively image the development of this condition would be invaluable in identifying critical stages when cachexia becomes life-threatening. Current multimodality molecular and functional imaging capabilities provide unique opportunities to study cachexia holistically in preclinical models and clinically. In this review we have provided examples of how state-of-the-art imaging techniques in combination with molecular characterization can be used to understand cancer-induced cachexia. SUMMARY: Such studies will lead to clinically translatable indices for the early detection of this condition and will identify novel targets to inhibit the cachexia cascade.
Indexed as
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.