Evidence map›Paper›PMID 21986826›Full record

ArticleAntimicrobial agents and chemotherapy2012

ICESp2905, the erm(TR)-tet(O) element of Streptococcus pyogenes, is formed by two independent integrative and conjugative elements.

Eleonora Giovanetti, Andrea Brenciani, Erika Tiberi, Alessandro Bacciaglia, Pietro Emanuele Varaldo

Open access · bronzeAbstract read
In one paragraph

Article in Antimicrobial agents and chemotherapy, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed
3.5field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 38 citations in OpenAlex.

  1. Characterization of a novel composite ICE inFrontiers in microbiology · 2026
    Article
  2. Article
  3. Article
  4. Tetracycline Resistance Mediated byAntimicrobial agents and chemotherapy · 2021
    Article
  5. Article
  6. Chromosomal Conjugative and Mobilizable Elements inPathogens (Basel, Switzerland) · 2019
    Article
  7. Antimicrobial Resistance inMicrobiology spectrum · 2018
    Review
  8. Article
  9. Review
  10. Genomic analysis of aNew microbes and new infections · 2017
    Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Molecular epidemiology and genomics of group A Streptococcus.Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases · 2015
    Review
  17. Review
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Eleonora GiovanettiDepartment of Biomedical Sciences, Section of Microbiology, Marche Polytechnic University, Ancona, Italy.
Andrea Brenciani
Erika Tiberi
Alessandro Bacciaglia
Pietro Emanuele Varaldo
Marche Polytechnic University · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In ICESp2905, a widespread erm(TR)- and tet(O)-carrying genetic element of Streptococcus pyogenes, the two resistance determinants are contained in separate fragments inserted into a scaffold of clostridial origin. ICESp2905 (∼65.6 kb) was transferable not only in its regular form but also in a defective form lacking the erm(TR) fragment (ICESp2906, ∼53.0 kb). The erm(TR) fragment was also an independent integrative and conjugative element (ICE) (ICESp2907, ∼12.6 kb). ICESp2905 thus results from one ICE (ICESp2907) being integrated into another (ICESp2906).

Indexed as

Genes, BacterialTetracycline ResistanceAnti-Bacterial AgentsBase SequenceChromosome MappingChromosomes, BacterialConjugation, GeneticDNA, BacterialDNA, CircularErythromycinHumansMicrobial Sensitivity TestsMolecular Sequence DataOpen Reading FramesSequence Analysis, DNAStreptococcal InfectionsAnti-Bacterial AgentsDNA, BacterialDNA, CircularErythromycinTetracycline

Identifiers

PMID21986826
PMCPMC3256084
OpenAlexW2101218955

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.