Evidence map›Paper›PMID 21986641›Full record

ArticleMolecular biology reports2012

EST dataset of pituitary and identification of somatolactin and novel genes in Chinese sturgeon, Acipenser sinensis.

Hong Cao, Xiaoqian Leng, Chuangju Li, Qiwei Wei, Jianfang Gui, Hanhua Cheng, Rongjia Zhou

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Article in Molecular biology reports, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

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0cells of the map it votes in
3citing papers in PubMed
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1 · What the graph read from it

What it found

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2 · The registry

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3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

7 authors.

Hong CaoDepartment of Genetics, College of Life Sciences, Wuhan University, Wuhan, 430072, China.
Xiaoqian Leng
Chuangju Li
Qiwei Wei
Jianfang Gui
Hanhua Cheng
Rongjia Zhou

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Chinese sturgeon (Acipenser sinensis) is a rare and endangered species and also an important resource for the sturgeon aquaculture industry, however, a few genes have been identified in this species. We report here construction of a pituitary cDNA library from a 24 years old female Chinese sturgeon just after its spawning, and obtained 2,025 ESTs from the library. 885 unique sequences were identified, which were categorized into 12 functional groups. More than half of the unique sequences (57%) do not match with annotated sequences in the public databases. Three of these novel genes were further identified. Notably, a full-length of cDNA (1,143 bp) encoding somatolactin of 232 amino acids was identified. Phylogenetic analysis showed 97% amino acid identity with White sturgeon somatolactin. RT-PCR analysis indicated that the somatolactin mRNA was only detected in pituitary. Pituitary-specific expression of the somatolactin suggested that the protein may play important physiological functions in pituitary-endocrine system of the Chinese sturgeon.

Indexed as

Databases, GeneticExpressed Sequence TagsAmino Acid SequenceAnimalsChinaDNA, ComplementaryFemaleFishesFish ProteinsGene Expression ProfilingGlycoproteinsMolecular Sequence DataOrgan SpecificityPhylogenyPituitary GlandPituitary HormonesDNA, ComplementaryFish ProteinsGlycoproteinsPituitary HormonesRNA, Messengersomatolactin protein, fish

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.