ReviewExpert review of cardiovascular therapy2011
Symptomatic and asymptomatic carotid artery plaque.
Review in Expert review of cardiovascular therapy, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 75 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Use of in Vivo 3T MR to Characterize Carotid Plaque in Patients and Correlate MR Findings With Symptoms
Burden Fatty Liver Among Acute Ischemic Cerebral Stroke Patients
Who cites it
75 citing papers in PubMed, 183 citations in OpenAlex.
- Evaluation of the effect of tofogliflozin on the tissue characteristics of the carotid wall-a sub-analysis of the UTOPIA trial.Cardiovascular diabetology · 2022Trial
- Smooth Muscle Cell Plasticity as a Central Determinant of Plaque Stability.Current atherosclerosis reports · 2026Review
- Cholesterol crystal formation and embolism in the central nervous system and their potential role in Alzheimer's disease.American heart journal plus : cardiology research and practice · 2026Article
- Plaque-level machine-learning prediction of carotid plaque vulnerability on computed tomography angiography.Neuroradiology · 2026Article
- Predictors of Late Adverse Outcomes After Carotid Endarterectomy.Medicina (Kaunas, Lithuania) · 2026Article
- Advancements in dual-targeting nanoparticle strategies for enhanced atherosclerosis therapy: Overcoming limitations of single-targeting approaches.Bioactive materials · 2026Review
- Spatial Myeloid Landscape of Large Artery Atherosclerotic and Cardioembolic Thrombi Retrieved by Mechanical Thrombectomy.FASEB journal : official publication of the Federation of American Societies for Experimental Biology · 2025Article
- Simultaneous carotid ultrasound and transcranial Doppler to detect cholesterol crystal emboli from unstable carotid plaque to the brain.American heart journal plus : cardiology research and practice · 2025Article
- Understanding thromboembolus transport patterns in the brain for stroke in the presence of carotid artery stenosis.PLoS computational biology · 2025Article
- Emerging cytokines contribute to the clinical manifestation of carotid artery plaque formation and stability in patients with diabetes.Atherosclerosis plus · 2025Article
- The formation of cholesterol crystals and embolization during myocardial infarction.American heart journal plus : cardiology research and practice · 2025Article
- Assessment of Inflammatory and Oxidative Stress Biomarkers for Predicting of Patients with Asymptomatic Carotid Artery Stenosis.Journal of clinical medicine · 2025Article
- Biomechanical assessment of vulnerable plaque: from histological evidence to ultrasound elastography and image-based computational patient-specific modelling.Frontiers in bioengineering and biotechnology · 2025Article
- Membrane vesicles from Red Complex bacteria: key players in oral pathogenesis, immune disruption, systemic diseases, and therapeutic insights.Frontiers in oral health · 2025Review
- Using machine learning to predict carotid artery symptoms from CT angiography: A radiomics and deep learning approach.European journal of radiology open · 2024Article
- The role of cholesterol crystals and ocular crystal emboli in retinal pathology.American heart journal plus : cardiology research and practice · 2024Article
- Diagnostic Methods of Atherosclerotic Plaque and the Assessment of Its Prognostic Significance-A Narrative Review.Journal of cardiovascular development and disease · 2024Review
- Association of subclinical carotid artery atherosclerosis assessed by carotid ultrasound with nonalcoholic fatty liver disease fibrosis score in young and middle-aged men.The international journal of cardiovascular imaging · 2024Article
- Use of intermediate cervical plexus block in carotid endarterectomy -an alternative to deep cervical plexus block: a case series.BMC anesthesiology · 2024Article
- CACSNet for automatic robust classification and segmentation of carotid artery calcification on panoramic radiographs using a cascaded deep learning network.Scientific reports · 2024Article
15 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 4 institutions in 3 countries.
Funding
Abstract
Carotid atherosclerotic plaques represent both stable and unstable atheromatous lesions. Atherosclerotic plaques that are prone to rupture owing to their intrinsic composition such as a large lipid core, thin fibrous cap and intraplaque hemorrhage are associated with subsequent thromboembolic ischemic events. At least 15-20% of all ischemic strokes are attributable to carotid artery atherosclerosis. Characterization of plaques may enhance the understanding of natural history and ultimately the treatment of atherosclerotic disease. MRI of carotid plaque and embolic signals during transcranial Doppler have identified features beyond luminal stenosis that are predictive of future transient ischemic attacks and stroke. The value of specific therapies to prevent stroke in symptomatic and asymptomatic patients with severe carotid artery stenosis are the subject of current research and analysis of recently published clinical trials that are discussed in this article.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.